What Factors Influence the Rate Constant of Substrate Epoxidation by Compound I of Cytochrome P450 and Analogous Iron(IV)-Oxo Oxidants?

The cytochromes P450 are a versatile range of mono-oxygenase enzymes that catalyze a variety of different chemical reactions, of which the key reactions include aliphatic hydroxylation and C=C double bond epoxidation. To establish the fundamental factors that govern substrate epoxidation by these en...

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Publicado en:	Journal of the American Chemical Society Vol. 132; no. 22; pp. 7656 - 7668
Autores principales:	Kumar, Devesh, Karamzadeh, Baharan, Sastry, G. Narahari, de Visser, Sam P.
Formato:	Artículo
Publicado:	American Chemical Society 6/9/2010
Materias:	Substrates (Materials science) Oxygenases Enzymes Chemical reactions Hydroxylation Density functionals Ionization (Atomic physics) Heme
Acceso en línea:	Ver este registro en EBSCOhost