Severe brain co-infection by cryptococcus neoformans and mycobacterium tuberculosis as a consequence of a non-bacillary lung tuberculosis.
An exceptionally rare case of concurrent central nervous system infection by clyptococcus neoformans and mycobacterium tuberculosis in a 25-year-old otherwise healthy Chinese student who very recently joined Italian post-doctoral courses is described, together with diagnostic and therapeutic difficu...
| Publicado en: | Archivos de Neurociencias Vol. 14; no. 3; pp. 192 - 196 |
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| Autores principales: | , |
| Formato: | Case Study |
| Publicado: |
Instituto Nacional de Neurologia y Neurocirugia, Departamento de Publicaciones Cientificas
jul-sep2009
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | An exceptionally rare case of concurrent central nervous system infection by clyptococcus neoformans and mycobacterium tuberculosis in a 25-year-old otherwise healthy Chinese student who very recently joined Italian post-doctoral courses is described, together with diagnostic and therapeutic difficulties encountered in a six-month-long hospitalization period, when only transient and/or negligible immune system impairments were detected. A non-bacillary pulmonary tuberculosis probably preceded and prompted both brain complications. This episode of very infrequent concurrent infections, should enforce the need of maintaining an elevated clinical suspicion for opportunistic infections and tuberculosis, even in absence of an obvious immunodeficiency, and related epidemiological clues. Un caso exepcionalmente raro de una infección por cryptococcus neoformans y mycobacterium tuberculosis en un hombre de 25 años, estudiante chino sano que recientemente se había incorporado a un curso postdoctoral. Se describen las dificultades para el diagnóstico y la terapéutica en un periodo de hospitalización de seis meses durante la cual sólo se encontraron ligeros cambios en su sistema inmunológico. Una tuberculosis pulmonar no bacilar quizás precedio las complicaciones. Este episodio de infección poco frecuente acentua la necesidad de mantener la sospecha de infecciones oportunistas y tuberculosis en ausencia de inmunodeficiencia o datos epidemiológicos. |
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