A Review of Sentinel Laboratory Performance Identification and Notification of Bioterrorism Agents.
Context.--The anthrax incident of 2001 in the United States prompted the College of American Pathologists (CAP), the Association of Public Health Laboratories, and the Centers for Disease Control and Prevention to develop exercises for Laboratory Response Network (LRN) sentinel laboratories. Objecti...
| Publicado en: | Archives of Pathology & Laboratory Medicine Vol. 134; no. 10; pp. 1490 - 1504 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | algorithm research tables/charts Journal Article |
| Publicado: |
College of American Pathologists
Oct2010
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=54639700&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 54639700 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00039985 1FS jtl: Archives of Pathology & Laboratory Medicine issn: 00039985 maglogo: N pubinfo: dt: Oct2010 vid: 134 iid: 10 pid: 2550 pub: College of American Pathologists place: Northfield, Illinois artinfo: ui: 54639700 54639700 105010159 10.5858/2010-0098-cp.1 54639700 ppf: 1490 ppct: 14 formats: fmt: @attributes: type: P tig: atl: A Review of Sentinel Laboratory Performance Identification and Notification of Bioterrorism Agents. aug: au: Wagar, Elizabeth A. Mitchell, Michael J. Carroll, Karen C. Beavis, Kathleen G. Petti, Cathy Anne Schlaberg, Robert Yasin, Bushra affil: Department of Laboratory Medicine, University of Texas, M. D. Anderson Cancer Center, Houston sug: subj: Bioterrorism Proficiency Testing, Laboratory Clinical Laboratories Public Health Administration Communicable Diseases Diagnosis Communicable Diseases Microbiology Human In Vitro Studies Descriptive Statistics Microbiological Techniques Bacillus Burkholderia Prospective Studies Yersinia Infections Klebsiella ab: Context.--The anthrax incident of 2001 in the United States prompted the College of American Pathologists (CAP), the Association of Public Health Laboratories, and the Centers for Disease Control and Prevention to develop exercises for Laboratory Response Network (LRN) sentinel laboratories. Objective.--To provide an overview of the results of the CAP bioterrorism Laboratory Preparedness Survey (LPS, 2007) and Laboratory Preparedness Exercise (LPX, 2008) and assist LRN sentinel laboratories and public health agencies in planning for bioterrorism events. Design.--Bioterrorism agents and nonbiothreat mimic organisms were provided in 2 mailings per year (2007 and 2008, 20 total challenges). Within each mailing, 2 to 3 agents were category A or category B bioterrorism agents (total of 10 categoric challenges). Some category A/B isolates were modified/vaccine strains. The total number of laboratories participating in these exercises ranged from 1316 to 1381. Isolate characteristics used to identify the organisms were compiled along with the participants' reporting actions. Educational commentary was provided with each exercise. Results.--Acceptable identification responses were as follows: Bacillus anthracis, 90% (2007) and 99.9% (2008); Yersinia pestis, 83.8% (2007) and 87.6% (2008); and Francisella tularensis subsp Holarctica, 86.6% (2007) and 91.6%(2008). The time interval between specimen receipt and notification of results to an LRN reference laboratory decreased from more than 10 days in 2007 to 3 or 4 days in 2008 for some challenges. Conclusions.--The bioterrorism challenge program (LPS, LPX) provides important comparative data from more than 1300 sentinel laboratories that can be used by individual laboratories to evaluate their identification and LRN reporting performance. pubtype: Academic Journal doctype: algorithm research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|