Diagnostic Concordance of Histologic Lung Cancer Type Between Bronchial Biopsy and Cytology Specimens Taken During the Same Bronchoscopic Procedure.
Context.--The diagnosis of lung cancer is often confirmed by cytology and biopsy specimens obtained during a bronchoscopic procedure. At our institution, these specimens are read by different pathologists, and the rate of concordance was not known. Objectives.--To evaluate the concordance rate in th...
| Published in: | Archives of Pathology & Laboratory Medicine Vol. 134; no. 10; pp. 1504 - 1513 |
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| Main Authors: | , , , , |
| Format: | case study pictorial research tables/charts Journal Article |
| Published: |
College of American Pathologists
Oct2010
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=54640086&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 54640086 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00039985 1FS jtl: Archives of Pathology & Laboratory Medicine issn: 00039985 maglogo: N pubinfo: dt: Oct2010 vid: 134 iid: 10 pid: 2550 pub: College of American Pathologists place: Northfield, Illinois artinfo: ui: 54640086 54640086 105010160 10.5858/2009-0363-oa.1 54640086 ppf: 1504 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Diagnostic Concordance of Histologic Lung Cancer Type Between Bronchial Biopsy and Cytology Specimens Taken During the Same Bronchoscopic Procedure. aug: au: Sackett, Melanie K. Salomão, Diva R. Donovan, Janis L. Yi, Eunhee S. Aubry, Marie Christine affil: Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota sug: subj: Cytodiagnosis Biopsy Specimen Handling Methods Carcinoma, Non-Small-Cell Lung Diagnosis Carcinoma, Non-Small-Cell Lung Pathology Carcinoma, Small Cell Diagnosis Carcinoma, Small Cell Pathology Clinical Competence Human Middle Age Aged Female Male Diagnostic Errors Retrospective Design Bronchoscopy Descriptive Statistics Pathologists Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Context.--The diagnosis of lung cancer is often confirmed by cytology and biopsy specimens obtained during a bronchoscopic procedure. At our institution, these specimens are read by different pathologists, and the rate of concordance was not known. Objectives.--To evaluate the concordance rate in the diagnosis of lung cancer types between cytology and biopsy specimens and to correlate discordancewith patient outcome. Design.--Specimens obtained during the same procedure, between January 1, 2000, and December 31, 2005, were identified. Cases with cytology and biopsy specimens positive for cancer were evaluated for concordance of histologic type, small cell versus non-small cell lung carcinoma. Cases with different types were considered discordant, and slides were reviewed. Results.--Of 231 cases, 225 (97.4%) had concordant diagnoses. Discordance was the result of misinterpretation of undifferentiated carcinoma, overinterpretation of squamous dysplasia, interpretation of suboptimal specimens with necrosis and crush artifact, and sampling error. Conclusions.--Even though the cytology and biopsy specimens were reviewed by different pathologists, the concordance rate for histologic type at our institution was high, emphasizing that this is a safe practice. The few discordant cases did not affect the patient's outcome. pubtype: Academic Journal doctype: case study pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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