The coagulopathy of cardiopulmonary bypass.

There have been numerous publications on the coagulopathy of cardiopulmonary bypass (CPB). This review provides an introduction to the history and main components of current CPB circuits and summarizes the current knowledge of pathogenesis, prevention, and treatment of the CPB coagulopathy. It encom...

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Publicado en:Critical Reviews in Clinical Laboratory Sciences Vol. 47; no. 5/6; pp. 197 - 213
Autores principales: Besser, Martin W., Klein, Andrew A.
Formato: algorithm pictorial review tables/charts Journal Article
Publicado: Taylor & Francis Ltd Sep-Dec2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep-Dec2010
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      pub: Taylor & Francis Ltd
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        atl: The coagulopathy of cardiopulmonary bypass.
      aug:
        au:
          Besser, Martin W.
          Klein, Andrew A.
        affil: Department of Haematology, Addenbrooke's Hospital, Cambridge, UK
      sug:
        subj:
          Cardiopulmonary Bypass Adverse Effects
          Postoperative Hemorrhage Prevention and Control
          Blood Coagulation Physiology
          Cardiopulmonary Bypass Methods
          Cardiopulmonary Bypass Equipment and Supplies
          Postoperative Hemorrhage Physiopathology
          Postoperative Hemorrhage Etiology
          Anticoagulants Therapeutic Use
          Blood Platelets Physiopathology
          Heparin Administration and Dosage
          Fibrinogen Analysis
          Blood Platelets Analysis
          Fibrinolysis
          Afibrinogenemia Therapy
          Blood Coagulation Tests
          Blood Transfusion
      ab: There have been numerous publications on the coagulopathy of cardiopulmonary bypass (CPB). This review provides an introduction to the history and main components of current CPB circuits and summarizes the current knowledge of pathogenesis, prevention, and treatment of the CPB coagulopathy. It encompasses an overview of intra- and postoperative monitoring of coagulation with special emphasis on the near-patient testing, its main complications, and the transfusion support, while taking into account the major changes in the technology used and supportive care provided since its inception.
      pubtype: Academic Journal
      doctype:
        algorithm
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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