Cardiovascular risk factors in first-degree relatives of patients with hypertension.
Objective: To evaluate the prevalence of cardiovascular risk factors (CRF) and absolute risk (AR) among first-degree consanguinity relatives of Colombian patients with hypertension. Methods: The study comprised 227 relatives (siblings and children of both sexes, between 12 and 40 years of age) and 2...
| Publicado en: | Colombia Medica Vol. 42; no. 1; pp. 17 - 26 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Universidad del Valle
ene-mar2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=61211701&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 61211701 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01208322 165D jtl: Colombia Medica issn: 01208322 maglogo: N pubinfo: dt: ene-mar2011 vid: 42 iid: 1 pid: 19876 pub: Universidad del Valle artinfo: ui: 61211701 61211701 104644915 61211701 ppf: 17 ppct: 9 formats: fmt: @attributes: type: P db: lth ui: 61211701 tig: atl: Cardiovascular risk factors in first-degree relatives of patients with hypertension. aug: au: LANDÁZURI, PATRICIA LOANGO, NELSY GALLEGO, MARTHA LUCÍA affil: Professor, Medicine Program, Faculty of Health, Universidad del Quindío, Armenia, Colombia sug: subj: Cardiovascular Risk Factors Epidemiology Hypertension Familial and Genetic Cardiovascular Diseases Familial and Genetic Colombia Nuclear Family Human Male Female Adolescence Child Young Adult Adult Middle Age Aged Aged, 80 and Over Risk Factors Prevalence Age Factors Smoking Epidemiology Cross Sectional Studies Descriptive Research Body Mass Index Confidence Intervals Chi Square Test Descriptive Statistics One-Way Analysis of Variance Data Analysis Software Sex Factors Sedentary Behavior Hypercholesterolemia Epidemiology Lipoproteins, HDL Cholesterol Blood Obesity Epidemiology Funding Source Adolescent: 13-18 years Child: 6-12 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Objective: To evaluate the prevalence of cardiovascular risk factors (CRF) and absolute risk (AR) among first-degree consanguinity relatives of Colombian patients with hypertension. Methods: The study comprised 227 relatives (siblings and children of both sexes, between 12 and 40 years of age) and 204 hypertensive patients 34-84 years old from Quindío, Colombia. Lipid profile, glycemia, smoking, body mass index, and blood pressure were analyzed, and the AR of cardiovascular disease (CVD) to 10 years was estimated. Relatives were divided into two groups: GF1 relatives ≤18 years, GF2 relatives >18 years. Results: three or more CRF were found in the three groups. The prevalence for smoking was 20.1%, 9.1%, and 15.9% in patients, GF1, and GF2, respectively. Hypercholesterolemia was 42.2%, 15.2%, and 18.6% in patients, GF1, and GF2, respectively. The prevalence of low HDL-c levels was 50.5%, 44.9%, and 63.6% in relatives, GF1, and GF2, respectively. Obesity was present alone in patients, (32.4%) and GF2 (10.8%). The AR was 19.6 and 6.4 in male and female patients, respectively; 0.31 and 0 in GF1 females and males, respectively, and in GF2 it was 1.5 and 0.15 in males and females, respectively. Conclusions: Patients and relatives had more than three CRFs. HDL-c was low in all three groups. The AR was high in the young relatives. Programs are needed for weight, smoking, sedentary and dyslipidemia control to prevent or delay the development of CVD in relatives. Objetivo: Evaluar la prevalencia de Factores de Riesgo Cardiovascular (FRC), y Riesgo Absoluto (RA) en familiares consanguíneos de pacientes colombianos hipertensos. Métodos: Se estudiaron 227 familiares (hermanos e hijos de ambos sexos, entre 12-40 años de edad), y 204 pacientes hipertensos (34-84 años) del Quindío, Colombia. Los familiares se dividieron en dos: grupo de familiares ≤18 años (GF1) y grupo de familiares >18 años (GF2). Se analizaron perfil lipídico, glicemia, tabaquismo e índice de masa corporal y se calculó el RA de sufrir enfermedad cardiovascular (ECV) a 10 años. Resultados: Se encontraron tres o más FRC en los tres grupos (pacientes, GF1 y GF2). La prevalencia de tabaquismo fue 20.1% 9.1% y 15.9% en pacientes, GF1 y GF2 respectivamente. La hipercolesterolemia fue 42.2% 15.2% y 18.6% en pacientes, GF1 y GF2 respectivamente. La prevalencia de niveles bajos de c-HDL fue 50.5%, 44.9% y 63.6% en familiares, GF1 y GF2, respectivamente. Mientras que la obesidad sólo estuvo presente en los pacientes (32.4%) y en el grupo GF2 (10.8%). El RA fue de 19.6 y 6.4 en los pacientes de género masculino y femenino, respectivamente; de 0.31 y 0 en el GF1 femenino y masculino, respectivamente; de 1.5 y 0.15 en el GF2 masculino y femenino, respectivamente. Conclusiones: Pacientes y familiares tenían más de tres FRC. El c-HDL fue bajo en los tres grupos. El RA fue alto en los familiares jóvenes. Se necesitan programas para el control de peso, tabaquismo, sedentarismo y dislipidemias para prevenir o retrasar el desarrollo de ECV en los familiares. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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