Intermediate-Assisted Multifunctional Catalysis in the Conversion of Flavin to 5,6-Dimethylbezimidazole by BluB: A Density Functional Theory Study.

BluB is a distinct flavin destructase that catalyzes a complex oxygen-dependent conversion of reduced flavin mononucleotide (FMNH) to form 5,6-dimethylbenzimidazole (DMB), the lower ligand of vitamin B. The catalyzed mechanism remains a challenge due to the discrepancy between the complexity of the...

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Publicado en:Journal of the American Chemical Society Vol. 133; no. 11; pp. 4079 - 4092
Autores principales: Xiao-Lei Wang, Jun-Min Quan
Formato: Artículo
Publicado: American Chemical Society 3/23/2011
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Acceso en línea:Ver este registro en EBSCOhost