Head circumference in ELBW babies is associated with learning difficulties and cognition but not ADHD in the school-aged child.
This study examines whether a small head circumference (HC) and low head-circumference growth velocity (HGV) during the first year of life predict consequences at school age in learning, cognition, and concentration. A total of 124 extremely-low-birthweight (ELBW) infants (birthweight 500 to 999 g)...
| Publicado en: | Developmental Medicine & Child Neurology Vol. 41; no. 6; pp. 375 - 381 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Jun1999
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=64877295&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 64877295 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00121622 1VN jtl: Developmental Medicine & Child Neurology issn: 00121622 maglogo: Y pubinfo: dt: Jun1999 vid: 41 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 64877295 64877295 NLM10400171 64877295 10.1111/j.1469-8749.1999.tb00622.x NLM10400171 64877295 ppf: 375 ppct: 6 formats: tig: atl: Head circumference in ELBW babies is associated with learning difficulties and cognition but not ADHD in the school-aged child. aug: au: Stathis, Stephen L O'Callaghan, Michael Harvey, Jacqueline Rogers, Yvonne Stathis, S L O'Callaghan, M Harvey, J Rogers, Y affil: Fellowship, Developmental Pediatrics sug: subj: Cognition Disorders Physiopathology Infant, Very Low Birth Weight Head Anatomy and Histology Learning Disorders Physiopathology Head Attention Deficit Hyperactivity Disorder Physiopathology Child, Preschool Prospective Studies Predictive Value of Tests Child Human Infant, Newborn Infant Validation Studies Comparative Studies Evaluation Research Multicenter Studies Questionnaires Scales Child, Preschool: 2-5 years Child: 6-12 years Infant, Newborn: birth-1 month Infant: 1-23 months ab: This study examines whether a small head circumference (HC) and low head-circumference growth velocity (HGV) during the first year of life predict consequences at school age in learning, cognition, and concentration. A total of 124 extremely-low-birthweight (ELBW) infants (birthweight 500 to 999 g) born between 1977 and 1986 were eligible for follow-up at the corrected ages of 4, 8, and 12 months and 2, 4, and 6 years. Infants were categorized as having a small HC (< 3% or 3 to 10%) on the basis of the 1990 British growth data which allowed standardized z-scores to be calculated for HC, independent of gestation and corrected age. HGV measurements were calculated using differences in the HC z-scores. In 1995, parents of 87 children agreed to participate in a study of learning and attention at school age. Attention-deficit-hyperactivity disorder (ADHD) was assessed using the Du Paul Rating Scale. Academic performances were based on a teacher questionnaire dealing with aspects of reading, writing, mathematics, and spelling. A child was considered to have a learning difficulty if academic problems were present in at least one of these four areas. Intellectual ability was assessed using the McCarthy Scale at 6 years. HC < 3% and 3 to 10% at 8 months' corrected age was strongly associated with school-aged learning problems (P=0.004), with a moderate specificity (70%), positive predictive value (PPV) (67%), and sensitivity (67%). HGV < or = 10% from birth to 4 months was also associated with learning problems at school age (P=0.01) with a higher specificity (98%) and PPV (88%) but lower sensitivity (20%). A logistic regression analysis was performed with the risk for learning difficulties at 8 months as the dependent variable. Sex, gestation, birthweight, multiple births, and a history of intraventricular hemorrhage did not substantially alter the unadjusted odds ratio (4.7; 95% CI 1.9 to 13.6). Maternal age and education did not confound the relation. No association was found between HC or HGV and ADHD. HC < 3% at 4 months (P<0.02), 8 months (P=0.02), and 12 months (P=0.04), and HGV between birth and 4 months (P<0.01) were significantly associated with low cognitive ability at 6 years. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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