How Adaptive Trial Designs Can Increase Efficiency in Psychiatric Drug Development: A Case Study.

This paper uses a recently completed study to illustrate how adaptive trial designs can increase efficiency of psychiatric drug development. The design employed allowed a continuous reassessment of the estimated dose-response such that patients were randomized in a double-blind fashion to one of sev...

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Bibliographic Details
Published in:Innovations in Clinical Neuroscience Vol. 8; no. 7; pp. 26 - 35
Main Authors: SHEN, JOAN, PRESKORN, SHELDON, DRAGALIN, VLADIMIR, SLOMKOWSKI, MARY, PADMANABHAN, S. KRISHNA, FARDIPOUR, PARVIN, SHARMA, AMARNATH, KRAMS, MICHAEL
Format: case study clinical trial research tables/charts Journal Article
Published: Matrix Medical Communications, LLC Jul2011
Online Access:View this record in EBSCOhost