Toward Bioinspired Galectin Mimetics: Identification of Ligand-Contacting Peptides by Proteolytic-Excision Mass Spectrometry.

Clinically relevant bioactivities of human galectins (adhesion/growth-regulatory galactoside-specific lectins) inspired the design of peptides as new tools to elicit favorable effects (e.g., in growth control) or block harmful binding (e.g., in tissue invasion). To obtain the bioinspired lead compou...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of the American Chemical Society Vol. 133; no. 38; pp. 14844 - 14848
Autores principales:	Moise, Adrian, André, Sabine, Eggers, Frederike, Krzeminski, Mickael, Przybylski, Michael, Gabius, Hans-Joachim
Formato:	Artículo
Publicado:	American Chemical Society 9/28/2011
Materias:	GABA agonists Ligand binding (Biochemistry) Lead compounds Proteolytic enzymes Carbohydrates Glycoproteins Phylogeny
Acceso en línea:	Ver este registro en EBSCOhost