Expanding the Genetic Code of an Animal.

Genetic code expansion, for the site-specific incorporation of unnatural amino acids into proteins, is currently limited to cultured cells and unicellular organisms. Here we expand the genetic code of a multicellular animal, the nematode Caenorhabditis elegans.

Detalles Bibliográficos
Publicado en:Journal of the American Chemical Society Vol. 133; no. 36; pp. 14196 - 14200
Autores principales: Greiss, Sebastian, Chin, Jason W.
Formato: Artículo
Publicado: American Chemical Society 9/14/2011
Materias:
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Genetic code expansion, for the site-specific incorporation of unnatural amino acids into proteins, is currently limited to cultured cells and unicellular organisms. Here we expand the genetic code of a multicellular animal, the nematode Caenorhabditis elegans.