Helicobacter pylori infection: a review of current scientific research on the efficacy or potential of herbal medicine for the treatment of H. pylori infection of the gastric mucosa.
Objective: To conduct a review of the current scientific literature on the efficacy of herbs in the treatment and eradication of Helicobacter pylori infection in the gastric mucosa. Methods: Research for scientific articles was obtained primarily through Medline and Google Scholar. A total of 53 sci...
| Publicado en: | Australian Journal of Medical Herbalism Vol. 23; no. 3; pp. 139 - 146 |
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| Autor principal: | |
| Formato: | research systematic review Journal Article |
| Publicado: |
National Herbalists Association of Australia (NHAA)
2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=66860180&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 66860180 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10338330 GUF jtl: Australian Journal of Medical Herbalism issn: 10338330 maglogo: N pubinfo: dt: 2011 vid: 23 iid: 3 pid: 12599 pub: National Herbalists Association of Australia (NHAA) artinfo: ui: 66860180 66860180 104591944 66860180 ppf: 139 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Helicobacter pylori infection: a review of current scientific research on the efficacy or potential of herbal medicine for the treatment of H. pylori infection of the gastric mucosa. aug: au: Williams, Lee sug: subj: Medicine, Herbal Helicobacter Infections Drug Therapy Gastric Mucosa Physiopathology Plants, Medicinal Therapeutic Use Treatment Outcomes Systematic Review Medline In Vitro Studies Human In Vivo Studies Cranberry Therapeutic Use Garlic Therapeutic Use Plant Extracts Therapeutic Use ab: Objective: To conduct a review of the current scientific literature on the efficacy of herbs in the treatment and eradication of Helicobacter pylori infection in the gastric mucosa. Methods: Research for scientific articles was obtained primarily through Medline and Google Scholar. A total of 53 scientific articles were examined, the vast majority of which were in vitro studies. Only one double blind randomised controlled study was identified involving the use of cranberry. Two controlled trials using garlic were also included. Results: Helicobacter pylori infection of the gastric mucosa is prevalent throughout the world, especially in countries of poor socioeconomic background. Infection has been proven to be a risk factor for the development of peptic ulcers, gastritis and in some cases adenocarcinoma or lymphoma. Eradication of the bacterial infection and treatment of symptoms due to infection are primarily treated with two antibiotics and a proton pump inhibitor however bacterial resistance to antibiotic therapy is now becoming a problem. A safe and cheap alternative treatment for this widespread infection is being sought. Current research shows that the use of herbs and herbal extracts for the treatment of Helicobacter pylori infection of the gastric mucosa has great potential. Unfortunately the majority of studies are in vitro with minimal in vivo studies currently being conducted. The most promising and most researched herbs for the treatment of H. pylori infection include cranberry and garlic. Garlic demonstrates strong antibacterial and antiadhesive actions against H. pylori and appears to have a synergistic action when used in conjunction with current orthodox antibiotic therapy. Cranberry inhibits H. pylori infection by preventing adhesion of the bacteria to the gastric mucosa and by acting as a bacteriostatic. Synergism between cranberry and antibiotic therapy with a proton pump inhibitor has been demonstrated. Licorice, green tea, cinnamon, chilli and numerous culinary herbs also demonstrate significant antibacterial or antiadhesive actions. Alcoholic extracts of herbs for the treatment of H. pylori infection appear to be most effective. With regard to herbal treatment, issues that need to be resolved with in vivo studies are herb extraction method, dosage, method of administration and length of time of treatment. pubtype: Academic Journal doctype: research systematic review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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