A Defense of Syntax-Based Gene Concepts in Postgenomics: Genes as Modular Subroutines in the Master Genomic Program.
The purpose of this article is to update and defend syntax-based (conserved DNA-sequence motifs) gene concepts. I show how syntax-based concepts have been and can be extended to accommodate complex cases of genome expression, regulation, and processing. In response to difficult cases and causal pari...
| Publicado en: | Philosophy of Science Vol. 78; no. 5; pp. 712 - 724 |
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| Formato: | Artículo |
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Cambridge University Press
Dec2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | The purpose of this article is to update and defend syntax-based (conserved DNA-sequence motifs) gene concepts. I show how syntax-based concepts have been and can be extended to accommodate complex cases of genome expression, regulation, and processing. In response to difficult cases and causal parity objections, I argue that the syntax-based approach fleshes out a deflationary concept that defines genes in terms of sequences and organizational features of the genome that contribute to a phenotype. |
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