Significantly lower prevalence of Helicobacter pylori in uremic patients than in patients with normal renal function.

The objective of the study was to evaluate the prevalence of Helicobacter pylori in patients with different degrees of renal function. Two hundred and twenty consecutive patients requiring gastroscopy for upper intestinal symptoms were enrolled in the study: group I (normal renal function, n = 127),...

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Publicado en:Journal of Gastroenterology Vol. 30; no. 5; pp. 585 - 589
Autores principales: Jaspersen, Daniel, Fassbinder, Winfried, Heinkele, Peter, Kronsbein, Hartmut, Schorr, Wolfgang, Raschra, Christoph, Brennenstuhl, Martin, Jaspersen, D, Fassbinder, W, Heinkele, P, Kronsbein, H, Schorr, W, Raschka, C, Brennenstuhl, M
Formato: clinical trial research Journal Article
Publicado: Springer Nature Oct1995
Acceso en línea:Ver este registro en EBSCOhost
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        09441174
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      jtl: Journal of Gastroenterology
      issn: 09441174
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    pubinfo:
      dt: Oct1995
      vid: 30
      iid: 5
      pid: 237
      pub: Springer Nature
      place: New York, New York
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        71069151
        71069151
        NLM8574329
        71069151
        10.1007/BF02367783
        NLM8574329
        71069151
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        atl: Significantly lower prevalence of Helicobacter pylori in uremic patients than in patients with normal renal function.
      aug:
        au:
          Jaspersen, Daniel
          Fassbinder, Winfried
          Heinkele, Peter
          Kronsbein, Hartmut
          Schorr, Wolfgang
          Raschra, Christoph
          Brennenstuhl, Martin
          Jaspersen, D
          Fassbinder, W
          Heinkele, P
          Kronsbein, H
          Schorr, W
          Raschka, C
          Brennenstuhl, M
        affil: Department of Gastroenterology, Academic Hospital, Pacelliallee 4-6 D-36043 Fulda Germany
      sug:
        subj:
          Gastritis Epidemiology
          Uremia Microbiology
          Helicobacter Infections Epidemiology
          Helicobacter Pylori
          Hemodialysis
          Uremia Therapy
          Prevalence
          Biopsy
          Human
          Gastroscopy
          Helicobacter Infections Complications
          Uremia Complications
          Retrospective Design
          Middle Age
          Gastritis Complications
          Clinical Trials
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Middle Aged: 45-64 years
      ab: The objective of the study was to evaluate the prevalence of Helicobacter pylori in patients with different degrees of renal function. Two hundred and twenty consecutive patients requiring gastroscopy for upper intestinal symptoms were enrolled in the study: group I (normal renal function, n = 127), group II (chronic renal failure, creatinine clearance > 5 < 90 ml/min, n = 59), and group III (hemodialysis therapy, n = 34). On endoscopy, biopsy specimens were taken for analysis of H. pylori infection by urease test and histology. The prevalence of H. pylori in patients with renal dysfunction proved to be significantly lower than that in patients with normal renal function (22.6% vs 37%, P < 0.05). The incidence of ulcer disease in patients with normal renal function was higher than that in uremic patients (14.2% vs 10.8%, not significant). These findings indicate that uremic patients seem to be partly protected against H. pylori infection.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        Journal Article
      ougenre: Article
    language: English
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