An open label non-comparative case series on the efficacy of an enzyme alginogel.
Objective: To evaluate the efficacy of an enzyme alginogel in outpatients with chronic or acute wounds left to heal by secondary intention. Method: This evaluation was a single-centre, single-arm, case series involving 23 patients with wounds of diverse aetiologies treated with the enzyme alginogel...
| Publicado en: | Journal of Wound Care Vol. 21; no. 1; pp. 22 - 28 |
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| Autor principal: | |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Mark Allen Holdings Limited
Jan2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=71819400&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 71819400 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09690700 H3U jtl: Journal of Wound Care issn: 09690700 maglogo: N pubinfo: dt: Jan2012 vid: 21 iid: 1 pid: 11383 pub: Mark Allen Holdings Limited artinfo: ui: 71819400 104521325 104521325 10.12968/jowc.2012.21.1.22 71819400 ppf: 22 ppct: 6 formats: fmt: @attributes: type: P tig: atl: An open label non-comparative case series on the efficacy of an enzyme alginogel. aug: au: Durante, C.M. affil: Wound Care Unit, Emergency Department, Army Military Hospital, Rome, Italy sug: subj: Enzymes Therapeutic Use Wounds, Chronic Therapy Wound Healing Case Studies Human Bandages and Dressings Italy Descriptive Statistics Visual Analog Scaling Wound Assessment Wilcoxon Signed Rank Test Data Analysis Software Pain ab: Objective: To evaluate the efficacy of an enzyme alginogel in outpatients with chronic or acute wounds left to heal by secondary intention. Method: This evaluation was a single-centre, single-arm, case series involving 23 patients with wounds of diverse aetiologies treated with the enzyme alginogel (Flaminal; Flen Pharma). The product was applied in accordance with the manufacturer's instructions and wounds were covered with secondary dressings. Treatment was based on a scheduled protocol and patients were assessed at days 14, 30 and 60. Results: Median baseline dimensions for the wounds were surface area 2.6cm2 and volume 2.8cm3. Median wound duration before application of the enzyme alginogel was 292 days, with 16 chronic wounds (78%). Three wounds were clinically infected at baseline; two were negative by day 14 and the third by day 30. After 2 months, wound surface area and volume had decreased, as could be expected. Two adverse events were reported: an allergic reaction in the skin surrounding the wound and transient maceration. Conclusion: The enzyme alginogel facilitated healing in chronic and acute wounds of diverse aetiologies. Additional research is warranted to confirm the clinical utility of the dressings in the management of chronic or acute wounds left to heal by secondary intention. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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