Antimicrobial resistance pattern of Gram-negative bacteria of nosocomial origin at a teaching hospital in the Islamic Republic of Iran.
The emergence of antimicrobial resistance is a global problem in the community and in hospitals. Antibiotic resistance of Gram-negative bacteria from nosocomial infections were evaluated during a 6-month period at Shariati teaching hospital, Tehran, Islamic Republic of Iran. Susceptibility tests wer...
| Publicado en: | Eastern Mediterranean Health Journal Vol. 18; no. 2; pp. 172 - 178 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
World Health Organization
Feb2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=74471726&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 74471726 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10203397 Z0U jtl: Eastern Mediterranean Health Journal issn: 10203397 maglogo: N pubinfo: dt: Feb2012 vid: 18 iid: 2 pid: 437 pub: World Health Organization artinfo: ui: 74471726 104555364 104555364 10.26719/2012.18.2.172 74471726 ppf: 172 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Antimicrobial resistance pattern of Gram-negative bacteria of nosocomial origin at a teaching hospital in the Islamic Republic of Iran. aug: au: Khalili, H. Soltani, R. Afhami, S Dashti-Khavidaki, S. Alijani, B. affil: Department of Clinical Pharmacy, School of Pharmacy; Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran sug: subj: Drug Resistance, Microbial Evaluation Academic Medical Centers Iran Cross Infection Risk Factors Gram-Negative Bacteria Analysis Gram-Negative Bacterial Infections Risk Factors Iran Human Data Analysis Software Odds Ratio Confidence Intervals Descriptive Statistics Adult Middle Age Aged Male Female Prospective Studies Multivariate Analysis Antiinfective Agents Drug Evaluation Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: The emergence of antimicrobial resistance is a global problem in the community and in hospitals. Antibiotic resistance of Gram-negative bacteria from nosocomial infections were evaluated during a 6-month period at Shariati teaching hospital, Tehran, Islamic Republic of Iran. Susceptibility tests were performed on 570 Gram-negative isolates obtained from clinical samples of patients infected after at least 72 hours stay in the hospital. Escherichia coli was the most frequently isolated Gram-negative organism (42.6%). The highest rate of resistance in Gram-negative isolates was seen in the intensive care unit, with Acinetobacter spp. as the most resistant organisms. Gentamicin was the most effective antibiotic against E. coli and all other isolates, while ciprofloxacin was also effective against a wide range of other species. Antibiotic resistant Gram-negative nosocomial infection is prevalent in this teaching hospital in Tehran. La résistance aux antimicrobiens est un problème mondial pour la population comme pour les hôpitaux. La résistance aux antibiotiques des bactéries à Gram négatif responsables d'infections nosocomiales a été évaluée pendant six mois à l'hôpital universitaire Shariati, à Téhéran (République islamique d'Iran). Des épreuves de sensibilité ont été réalisées sur 570 isolats à Gram négatif obtenus à partir d'échantillons cliniques prélevés chez des patients infectés ayant passé au moins 72 heures à l'hôpital. La bactérie à Gram négatif la plus fréquemment isolée était Escherichia coli (42,6 % des échantillons). Le taux de résistance le plus élevé a été observé dans l'unité de soins intensifs, Acinetobacter spp. étant l'organisme le plus résistant. La gentamicine était l'antibiotique le plus efficace contre E. coli et contre tous les autres isolats, mais la ciprofloxacine était également efficace contre un large spectre d'autres espèces. Les infections nosocomiales dues à des bactéries à Gram négatif résistantes aux antibiotiques sont fréquentes dans cet hôpital universitaire de Téhéran. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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