Comparative Analysis of Protein Networks: Hard Problems, Practical Solutions.
The article focuses on the use of comparative analysis tools to study protein networks and determine the function and interplay among cellular molecular components. It states that the comparative analysis of networks from multiple species has been effective in detecting significant biological patter...
| Publicado en: | Communications of the ACM Vol. 55; no. 5; pp. 88 - 98 |
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| Formato: | Artículo |
| Publicado: |
Association for Computing Machinery
May2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=74716742&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 74716742 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00010782 ACM jtl: Communications of the ACM issn: 00010782 maglogo: N pubinfo: dt: May2012 vid: 55 iid: 5 pid: 68 pub: Association for Computing Machinery artinfo: ui: 74716742 10.1145/2160718.2160738 ppf: 88 ppct: 10 formats: tig: atl: Comparative Analysis of Protein Networks: Hard Problems, Practical Solutions. aug: su: Comparative studies Protein research Molecules Integer programming Heuristic programming Isomorphism (Mathematics) Graphic methods sug: subj: Comparative studies Protein research Molecules Integer programming Heuristic programming Isomorphism (Mathematics) Graphic methods ab: The article focuses on the use of comparative analysis tools to study protein networks and determine the function and interplay among cellular molecular components. It states that the comparative analysis of networks from multiple species has been effective in detecting significant biological patterns conserved across species. It suggests that a combination of heuristic, parametrized, and integer programming-based approaches can be used to solve computational challenges such as graph and subgraph isomorphism along with the detection of heavy subgraphs. pubtype: Periodical doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y dt: @attributes: year: 2012 holdings: @attributes: islocal: N |
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