Dyspnoea and mortality in older people in the community: a 10-year follow-up.
Background: examine baseline dyspnoea and subsequent 10-year mortality adjusting for age and gender and determine whether dyspnoea is related to early or late mortality or both. Examine the relationship between dyspnoea and mortality adjusting for confounding effects of underlying diseases.Methods:...
| Publicado en: | Age & Ageing Vol. 41; no. 4; pp. 545 - 550 |
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| Autores principales: | , , |
| Formato: | Artículo |
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Oxford University Press / USA
Jul2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=77233824&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 77233824 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Jul2012 vid: 41 iid: 4 pid: 622 pub: Oxford University Press / USA artinfo: ui: 77233824 10.1093/ageing/afs049 ppf: 545 ppct: 5 formats: tig: atl: Dyspnoea and mortality in older people in the community: a 10-year follow-up. aug: au: Ahmed, Tanvir Steward, John A. O'Mahony, M. Sinead affil: Geriatric Department , University Hospital of Llandough , Cardiff , UK Public Health , Welsh Cancer Intelligence and Surveillance Unit, Public Health Wales , Cardiff , UK su: Wales Epidemiology Old age Mortality risk factors Dyspnea Echocardiography Electrocardiography Pulmonary function tests Questionnaires Research funding Statistical sampling Scales (Weighing instruments) Logistic regression analysis Data analysis Proportional hazards models Data analysis software Kaplan-Meier estimator sug: subj: Epidemiology Old age Wales Marketing Research and Public Opinion Polling All other general-purpose machinery manufacturing Scale and Balance Manufacturing Mortality risk factors Dyspnea Echocardiography Electrocardiography Pulmonary function tests Questionnaires Research funding Statistical sampling Scales (Weighing instruments) Logistic regression analysis Data analysis Proportional hazards models Data analysis software Kaplan-Meier estimator keyword: dyspnoea elderly mortality older people dyspnoea elderly mortality older people ab: Background: examine baseline dyspnoea and subsequent 10-year mortality adjusting for age and gender and determine whether dyspnoea is related to early or late mortality or both. Examine the relationship between dyspnoea and mortality adjusting for confounding effects of underlying diseases.Methods: we sent modified Medical Research Council (MRC) dyspnoea questionnaire to identify breathlessness in 1,404 randomly selected subjects from general practitioner lists of 5,002 subjects aged 70 years and over living in the community. A further random sample of 500 subjects underwent clinical assessment including pulmonary function tests, electrocardiography and echocardiography. Subjects were followed up for 10 years and all deaths were recorded, using general practitioner records and the local death registry.Results: prevalence of dyspnoea was 32.3%. Breathlessness was associated with early mortality and late mortality. At 2 years 10.1% breathless subjects died compared with 3.4% non-breathless (P = 0.02). At 10 years 63.3% breathless had died compared with 40.5% non-breathless (P = 0.0001). Increasing grade of MRC dyspnoea was associated with 10 mortality. Advancing age (OR: 2.27), male gender (OR: 1.95), breathlessness (OR: 2.53), left ventricular dysfunction (OR: 5.01) and chronic airways disease (OR: 3.04) were all significantly associated with 10-year mortality. After adjustment of age, gender and underlying diseases breathlessness was associated with 10-year mortality (P = 0.02).Conclusion: dyspnoea is a predictor of early and late mortality and increasing grade of dyspnoea is associated with a higher rate of mortality. Dyspnoea is an independent risk factor for mortality after adjustment for age, gender and underlying diseases. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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