Prostatic carcinoma in dog. Case report.

Dogs and humans are the only species that with a certain degree of frequency develop naturally prostatic carcinoma. The prostatic carcinoma (PC) is a neoplasia which originates from the glandular epithelium of the prostate. In dogs, the frequency of appearance varies from 0.29 to 0.6% and there is n...

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Publicado en:Veterinaria México Vol. 43; no. 2; pp. 175 - 184
Autores principales: Campuzano-Granados, Jaime, Mancera-Padilla, Mónica Yunuhent, Reyes-Matute, Alonso
Formato: Artículo
Publicado: Facultad de Medicina Veterinaria y Zootecnia UNAM abr-jun2012
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: abr-jun2012
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      pub: Facultad de Medicina Veterinaria y Zootecnia UNAM
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        atl: Prostatic carcinoma in dog. Case report.
      aug:
        au:
          Campuzano-Granados, Jaime
          Mancera-Padilla, Mónica Yunuhent
          Reyes-Matute, Alonso
        affil: Departamento de Patología Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Circuito Exterior, Coyoacán, 04510, México, DF
      su:
        Prostate cancer
        Cancer in animals
        Dog diseases
        Epithelium
        Cancer susceptibility
        Metastasis
        Ultrastructure (Biology)
      sug:
        subj:
          Prostate cancer
          Cancer in animals
          Dog diseases
          Epithelium
          Cancer susceptibility
          Metastasis
          Ultrastructure (Biology)
      keyword:
        CARCINOMA
        DOGS
        METASTASIS
        PROSTATE
      ab: Dogs and humans are the only species that with a certain degree of frequency develop naturally prostatic carcinoma. The prostatic carcinoma (PC) is a neoplasia which originates from the glandular epithelium of the prostate. In dogs, the frequency of appearance varies from 0.29 to 0.6% and there is no evidence of predisposition factors that favor its development; in humans there are a considerable number of factors that can be observed, like fat rich diets, genetics, among other causes. Four histological patterns have been described in dogs: tufting, micropapillar, cribriform and flat, being the former the most common. These tumors have a high metastatic rate, being the sites of incidence the regional lymph nodes, lungs and bones. The present case corresponds to an 11 year old Labrador dog that began with anorexia, prostration and lameness of the left pelvic member (LPM), progressive deterioration and no response to treatment; it had to be euthanized and necropsy was performed. At the macroscopic examination, the most outstanding findings were thrombosis in jugular veins, generalized lymph node enlargement and multiple mineralization zones in the muscles that surround the left pelvic member. Whereas in the prostate, multiple white yellowish well delimited nodules from 0.5 to 0.7 cm in diameter were found. Such nodules were constituted by neoplastic glandular epithelial cells. These cells were observed invading blood and lymphatic vessels of different organs, like muscles, skin, lung, liver, kidney, intestines, testicles and meninges. The final diagnosis of prostatic carcinoma was determined by the histological and ultrastructural characteristics and biological behavior.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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