Frontal Brain Asymmetry in Depression With Comorbid Anxiety: A Neuropsychological Investigation.
The approach-withdrawal model posits that depression and anxiety are associated with a relative right asymmetry in frontal brain activity. Most studies have tested this model using measures of cortical brain activity such as electroencephalography. However, neuropsychological tasks that differential...
| Publicado en: | Journal of Abnormal Psychology Vol. 121; no. 3; pp. 579 - 592 |
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| Autores principales: | , , , , , |
| Formato: | Artículo |
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American Psychological Association
Aug2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=79287116&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 79287116 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 0021843X JAP jtl: Journal of Abnormal Psychology issn: 0021843X maglogo: N pubinfo: dt: Aug2012 vid: 121 iid: 3 pid: 34 pub: American Psychological Association artinfo: ui: 79287116 10.1037/a0027587 ppf: 579 ppct: 13 formats: tig: atl: Frontal Brain Asymmetry in Depression With Comorbid Anxiety: A Neuropsychological Investigation. aug: au: Nelson, Brady D. Sarapas, Casey Robison-Andrew, E. Jenna Altman, Sarah E. Campbell, Miranda L. Shankman, Stewart A. affil: Department of Psychology, University of Illinois, 1007 West Harrison Street, Room 1062D, Chicago, IL 60607 su: Mental depression Anxiety Neuropsychology Brain function localization Cerebral cortex Electroencephalography Performance evaluation sug: subj: Mental depression Anxiety Neuropsychology Brain function localization Cerebral cortex Electroencephalography Performance evaluation keyword: anxiety asymmetry depression fluency neuropsychology anxiety asymmetry depression fluency neuropsychology ab: The approach-withdrawal model posits that depression and anxiety are associated with a relative right asymmetry in frontal brain activity. Most studies have tested this model using measures of cortical brain activity such as electroencephalography. However, neuropsychological tasks that differentially use left versus right frontal cortical regions can also be used to test hypotheses from the model. In two independent samples (Study 1 and 2), the present study investigated the performance of currently depressed individuals with or without a comorbid anxiety disorder and healthy controls on neuropsy-chological tasks tapping primarily left (verbal fluency) or right (design fluency) frontal brain regions. Across both samples, results indicated that comorbid participants performed more poorly than depressed only and control participants on design fluency, while all groups showed equivalent performance on verbal fluency. Moreover, comorbid participants showed "asymmetrical" performance on these two tasks (i.e., poorer design [right frontal] relative to verbal [left frontal] fluency), whereas depressed only and control participants showed approximately symmetrical profiles of performance. Results from these two samples suggest an abnormal frontal asymmetry in neurocognitive performance driven primarily by right frontal dysfunction among anxious-depressed individuals and highlight the importance of considering comorbid anxiety when examining frontal brain functioning in depression. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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