The effect of radioiodine on eradication of Helicobacter pylori infection in patients with thyroid cancer—A pilot study
Recently, 32% of Helicobacter pylori (H pylori) infected patients who were treated for differentiated thyroid carcinoma (DTC) were found to have a negative urease breath test at 2 months posttreatment. Our objectives were to eradication of clarify equivocal findings, and determine whether radioiodin...
| Publicado en: | Operative Techniques in Otolaryngology - Head & Neck Surgery Vol. 23; no. 3; pp. 206 - 211 |
|---|---|
| Autores principales: | , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
W B Saunders
Sep2012
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=79809956&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 79809956 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10431810 DP6 jtl: Operative Techniques in Otolaryngology - Head & Neck Surgery issn: 10431810 maglogo: N pubinfo: dt: Sep2012 vid: 23 iid: 3 pid: 1351 pub: W B Saunders place: Philadelphia, Pennsylvania artinfo: ui: 79809956 104504595 104504595 10.1016/j.otot.2012.03.001 79809956 ppf: 206 ppct: 5 formats: tig: atl: The effect of radioiodine on eradication of Helicobacter pylori infection in patients with thyroid cancer—A pilot study aug: au: Shmuely, Haim Friedman, Michael Aronov, Igor Bernstine, Hanna Yahav, Jacob Samra, Zmira Chodick, Gabriel Hamilton, Craig S. Samuelson, Christian G. Groshar, David affil: Department of Internal Medicine, Rabin Medical Center, Beilinson Hospital, Petah Tiqwa and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel sug: subj: Iodine Helicobacter Infections Diagnosis Radioisotopes Pilot Studies Human Thyroid Neoplasms Israel ab: Recently, 32% of Helicobacter pylori (H pylori) infected patients who were treated for differentiated thyroid carcinoma (DTC) were found to have a negative urease breath test at 2 months posttreatment. Our objectives were to eradication of clarify equivocal findings, and determine whether radioiodine eradicates this chronic bacterial infection. Twenty-eight patients (25 DTC patients and 3 with hyperthyroidism) positive for H pylori stool antigen were treated with oral radioiodine (131I) at a dose of 100 to 200 mCi in 18 patients with thyroid carcinoma; 30 mCi in 1 patient with a significant residual mass in the thyroid bed after surgery; and 4 mCi in 6 patients who had been treated with 100 to 150 mCi over the last 5 years. The hyperthyroid patients received 10 to 20 mCi. To standardize the results, and better compare with a previous study, only those patients who received a dose of 100 to 200 mCi were included for analysis. All 18 DTC patients who tested positive for H pylori stool antigen before radioiodine treatment remained positive 3 months posttreatment, indicating an eradication rate of 0% with an upper 95% confidence limit of 18.53%. Radioiodine administered to H pylori infected patients did not eradicate infection in Israeli patients. pubtype: Periodical doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|