Acinetobacter meningitis in post neurosurgical patients: epidemiology, antimicrobial resistance, treatment options and risk factors that predict the outcome.

Introduction: Post-operative meningitis caused by Acinetobacter sp. though a rare occurrence is a serious complication in neurosurgical ICUs. These are opportunistic organisms implicated in hospital-acquired infections. Aim: The aim was to study the epidemiology, the resistance pattern and the risk...

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Publicado en:Canadian Journal of Infection Control / Revue Canadienne de Prévention des Infections Vol. 27; no. 3; pp. 153 - 160
Autores principales: Bhargava, Aradhana, Mishra, Bibhabati, Thakur, Archana, Dogra, Vinita, Loomba, Poonam, Jain, Manisha, Gupta, Sonal, Banerjee, Priyanka, Haider, Mehvash
Formato: research tables/charts Journal Article
Publicado: Infection Prevention & Control Canada (IPAC Canada) Fall2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Fall2012
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      pub: Infection Prevention & Control Canada (IPAC Canada)
      place: Winnipeg, Manitoba
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        atl: Acinetobacter meningitis in post neurosurgical patients: epidemiology, antimicrobial resistance, treatment options and risk factors that predict the outcome.
      aug:
        au:
          Bhargava, Aradhana
          Mishra, Bibhabati
          Thakur, Archana
          Dogra, Vinita
          Loomba, Poonam
          Jain, Manisha
          Gupta, Sonal
          Banerjee, Priyanka
          Haider, Mehvash
        affil: Department of Microbiology, G B Pant Hospital, New Delhi
      sug:
        subj:
          Meningitis, Bacterial Epidemiology
          Acinetobacter Infections Epidemiology
          Postoperative Complications
          Surgical Patients
          Neurosurgery
          Risk Factors
          Drug Resistance, Microbial
          Cross Infection Etiology
          Data Analysis Software
          Meningitis, Bacterial Mortality
          Acinetobacter Infections Mortality
          Intensive Care Units
          India
          Cerebrospinal Fluid Microbiology
          Microbial Culture and Sensitivity Tests
          Acinetobacter Infections Drug Therapy
          Meningitis, Bacterial Drug Therapy
          Glasgow Coma Scale
          Scales
          Descriptive Statistics
          Adult
          Male
          Female
          Chi Square Test
          Human
          Length of Stay
          Adult: 19-44 years
          Male
          Female
      ab: Introduction: Post-operative meningitis caused by Acinetobacter sp. though a rare occurrence is a serious complication in neurosurgical ICUs. These are opportunistic organisms implicated in hospital-acquired infections. Aim: The aim was to study the epidemiology, the resistance pattern and the risk factors associated with the mortality in patients of post-operative Acinetobacter meningitis. Setting and design: Tertiary-care hospital and an observational study. Materials and methods: All patients with nosocomial post surgical meningitis due to Acinetobacter sp. between January 2008 and February 2010 were reviewed. Statistical analysis: It was performed by using Statistical Package for Social Sciences for Windows 12.0 Programme. Results: During the study period, 286 (8.71%) cases of post-operative meningitis were identified. (Total no. operated cases were 3283). Out of these 31 (10.84%) developed Acinetobacter baumannii meningitis. The mortality rates were 51.61% (16 patients). The risk factors which predict fatal outcome were underlying serious neurosurgical condition, presence of EVD and CVC, type and number of neurosurgical procedures, inappropriate antibiotic therapy, resistance to carbapenems, low Glasgow Coma score and inability to achieve sterilization of CSF. Most of the Acinetobacter strains were multi-drug resistant.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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