A Tetradentate Ligand for the Enantioselective Ti(IV)-Promoted Oxidation of Sulfides to Sulfoxides: Origin of Enantioselectivity.

A detailed stereomechanistic analysis has led to the design of a new tetradentate ligand for the enantioselective Ti(IV)-catalyzed oxidation of unsymmetrical sulfides to sulfoxides with high selectivity. The pathway of this oxidation and the closely related and long-known Kagan—Modena oxidation have...

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Publicado en:Journal of the American Chemical Society Vol. 134; no. 42; pp. 17354 - 17358
Autores principales: Newhouse, Timothy R., Xin Li, Blewett, Megan M., Whitehead, Clare M. C., Corey, E. J.
Formato: Artículo
Publicado: American Chemical Society 10/24/2012
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: A Tetradentate Ligand for the Enantioselective Ti(IV)-Promoted Oxidation of Sulfides to Sulfoxides: Origin of Enantioselectivity.
      aug:
        au:
          Newhouse, Timothy R.
          Xin Li
          Blewett, Megan M.
          Whitehead, Clare M. C.
          Corey, E. J.
        affil: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States
      su:
        Ligands (Chemistry)
        Enantioselective catalysis
        Oxidation
        Sulfides
        Sulfoxides
        Hydroperoxides
        Equilibrium constant (Chemistry)
      sug:
        subj:
          Ligands (Chemistry)
          Enantioselective catalysis
          Oxidation
          Sulfides
          Sulfoxides
          Hydroperoxides
          Equilibrium constant (Chemistry)
      ab: A detailed stereomechanistic analysis has led to the design of a new tetradentate ligand for the enantioselective Ti(IV)-catalyzed oxidation of unsymmetrical sulfides to sulfoxides with high selectivity. The pathway of this oxidation and the closely related and long-known Kagan—Modena oxidation have been clarified to identify the likely origin of the enantioselectivity.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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