Retrospective analysis of outcome data with regards to the use of Phisio®-, Bioline®- or Softline®-coated cardiopulmonary bypass circuits in cardiac surgery.

Background: Numerous cardiopulmonary bypass circuits with various coatings designed to reduce the inflammatory response and to provide better hemocompatibility are available. The aim of this study was to compare the effect of phosphorylcholine-coated, albumin-heparin-coated and synthetic polymer-coa...

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Publicado en:Perfusion Vol. 27; no. 6; pp. 530 - 535
Autores principales: Reser, D, Seifert, B, Klein, M, Dreizler, T, Hasenclever, P, Falk, V, Starck, C
Formato: research tables/charts Journal Article
Publicado: Sage Publications, Ltd. Nov2012
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Retrospective analysis of outcome data with regards to the use of Phisio®-, Bioline®- or Softline®-coated cardiopulmonary bypass circuits in cardiac surgery.
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        au:
          Reser, D
          Seifert, B
          Klein, M
          Dreizler, T
          Hasenclever, P
          Falk, V
          Starck, C
        affil: Clinic of Cardiac and Vascular Surgery, University Hospital Zurich, Zurich, Switzerland
      sug:
        subj:
          Cardiopulmonary Bypass Methods
          Treatment Outcomes
          Human
          Retrospective Design
          Equipment and Supplies Utilization
          Switzerland
          Middle Age
          Aged
          Data Analysis Software
          Kruskal-Wallis Test
          Chi Square Test
          Fisher's Exact Test
          Male
          Female
          Descriptive Statistics
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Numerous cardiopulmonary bypass circuits with various coatings designed to reduce the inflammatory response and to provide better hemocompatibility are available. The aim of this study was to compare the effect of phosphorylcholine-coated, albumin-heparin-coated and synthetic polymer-coated perfusion tubing systems on patient outcome. Methods: We performed a retrospective database review of elective patients between January 1st 2010 and December 31st 2010. Demographics, preoperative, operative, postoperative data and follow-up were collected and statistically analysed. Results: We identified 201 patients and formed three groups: Group 1 with phosphorylcholine coating (n=133), Group 2 with albumin-heparin coating (n=32) and Group 3 synthetic polymer coating (n=36). Mean age was 68±11years, additive Euroscore 5.8±2.7. In-hospital outcomes were comparable between the groups without statistically significant differences. The overall 30-day and 1-year late survival were 98.5% and 96.7±1.9%, respectively. Conclusions: Our findings suggest that in-hospital and follow-up outcomes are comparable in cardiac surgery patients after using either phosphorylcholine-coated, albumin-heparin-coated or synthetic polymer-coated circuits during cardiopulmonary bypass.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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