TNFα pathway blockade ameliorates toxic effects of FSGS plasma on podocyte cytoskeleton and β3 integrin activation.

Background: In the absence of mutant genes encoding components of the podocyte slit diaphragm, about 30-50 % of children with primary glucocorticoid-resistant focal segmental glomerulosclerosis (FSGS) develop recurrent proteinuria and slowly progressive FSGS lesions following renal transplantation....

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Publicado en:Pediatric Nephrology Vol. 27; no. 12; pp. 2217 - 2227
Autores principales: Bitzan, Martin, Babayeva, Sima, Vasudevan, Anil, Goodyer, Paul, Torban, Elena
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Dec2012
Acceso en línea:Ver este registro en EBSCOhost