Tissue engineered technologies: regulatory pharmaceuticalization in the European Union.

Human tissues and cells, and tissue engineered (TE) therapies, have been the object of attempts at regulatory regime-building in Europe since the late 1990s. As a sector-in-the-making, or technological zone, TE has been beset by multiple uncertainties. The 2007 Regulation on Advanced Therapy Medicin...

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Published in:Innovation: The European Journal of Social Sciences Vol. 25; no. 4; pp. 389 - 409
Main Author: Faulkner, Alex
Format: Article
Published: Taylor & Francis Ltd Dec2012
Subjects:
Online Access:View this record in EBSCOhost
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      dt: Dec2012
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      pub: Taylor & Francis Ltd
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        10.1080/13511610.2012.723333
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        atl: Tissue engineered technologies: regulatory pharmaceuticalization in the European Union.
      aug:
        au: Faulkner, Alex
        affil: Department of Political Economy, King's College London, Strand, London, WC2R 2LS, UK
      su:
        Europe
        European Union
        Technological innovations
        Tissue engineering
        Pharmaceutical industry
        Medical equipment industry
      sug:
        subj:
          Technological innovations
          Europe
          European Union
          Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers
          Professional machinery, equipment and supplies merchant wholesalers
          Surgical and Medical Instrument Manufacturing
          Medical equipment and supplies manufacturing
          Pharmaceutical Preparation Manufacturing
          Pharmaceutical and medicine manufacturing
          Pharmaceuticals and pharmacy supplies merchant wholesalers
          Drugs and Druggists' Sundries Merchant Wholesalers
          Tissue engineering
          Pharmaceutical industry
          Medical equipment industry
      keyword:
        innovation
        pharmaceuticalization
        regulation
        tissue-engineering
        innovation
        pharmaceuticalization
        regulation
        tissue-engineering
      ab: Human tissues and cells, and tissue engineered (TE) therapies, have been the object of attempts at regulatory regime-building in Europe since the late 1990s. As a sector-in-the-making, or technological zone, TE has been beset by multiple uncertainties. The 2007 Regulation on Advanced Therapy Medicinal Products, expands the legal scope of EU pharmaceutical jurisdiction to cover tissue engineering as “unconventional medicine”. This paper outlines the regulatory pathway taken by TE, explaining how the eventual pharmaceutical designation hides contentious, continuing stakeholder debates about the substantive definition of TE, its modes of production, tissue bank–hospital–industry relationships, the position of the medical device sector, and the appropriate type and institutional form of regulatory controls. In spite of the aim of providing “legal certainty”, the new regime has strategically built-in scope for future “technical” developments, and recent institutional innovations made by the key EU regulatory body respond to the continuing stakeholder tensions. The conclusion is that the EU Regulation provides some “regulatory ordering” of the TE zone while providing an open-ended flexibility, and inter-sectoral industry tensions continue given the shape of the recent EU legislation.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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