Low fat-free mass as a marker of mortality in community-dwelling healthy elderly subjects†.
Background: low fat-free mass has been related to high mortality in patients. This study evaluated the relationship between body composition of healthy elderly subjects and mortality.Methods: in 1999, 203 older subjects underwent measurements of body composition by bioelectrical impedance analysis,...
| Publicado en: | Age & Ageing Vol. 42; no. 1; pp. 33 - 40 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
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Oxford University Press / USA
Jan2013
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=84194850&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 84194850 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Jan2013 vid: 42 iid: 1 pid: 622 pub: Oxford University Press / USA artinfo: ui: 84194850 10.1093/ageing/afs091 ppf: 33 ppct: 7 formats: tig: atl: Low fat-free mass as a marker of mortality in community-dwelling healthy elderly subjects†. aug: au: Genton, Laurence Graf, Christophe E. Karsegard, Véronique L. Kyle, Ursula G. Pichard, Claude affil: University Hospital – Clinical Nutrition, Rue Gabrielle Perret-Gentil 4, Geneva 14 1211, Switzerland University Hospital – Internal Medicine, Rehabilitation and Geriatrics, Geneva, Switzerland Baylor College of Medicine – Pediatric Critical Care Medicine, Houston, TX, USA su: Anthropometry Mortality Old age Body composition Log-linear models Longitudinal method Questionnaires Research funding Scales (Weighing instruments) T-test (Statistics) Multiple regression analysis Data analysis software Descriptive statistics Kaplan-Meier estimator sug: subj: Anthropometry Mortality Old age All other general-purpose machinery manufacturing Scale and Balance Manufacturing Body composition Log-linear models Longitudinal method Questionnaires Research funding Scales (Weighing instruments) T-test (Statistics) Multiple regression analysis Data analysis software Descriptive statistics Kaplan-Meier estimator keyword: body composition fat-free mass fat-free mass index mortality older people body composition fat-free mass fat-free mass index mortality older people ab: Background: low fat-free mass has been related to high mortality in patients. This study evaluated the relationship between body composition of healthy elderly subjects and mortality.Methods: in 1999, 203 older subjects underwent measurements of body composition by bioelectrical impedance analysis, Charlson co-morbidity index and estimation of energy expenditure through physical activity by a validated questionnaire. These measurements were repeated in 2002, 2005 and 2008 in all consenting subjects. Mortality data between 1999 and 2010 were retrieved from the local death registers. The relationship between mortality and the last indexes of fat and fat-free masses was analysed by multiple Cox regression models.Results: women's and men's data at last follow-up were: age 81.1 ± 5.9 and 80.9 ± 5.8 years, body mass index 25.3 ± 4.6 and 26.1 ± 3.4 kg/m2, fat-free mass index 16.4 ± 1.8 and 19.3 ± 1.9 kg/m2 and fat mass index 9.0 ± 3.2 and 6.8 ± 2.0 kg/m2. Fifty-eight subjects died between 1999 and 2010. The fat-free mass index (hazard ratio 0.77; 95% confidence interval 0.63–0.95) but not the fat mass index, predicted mortality in addition to sex and Charlson index. The multiple Cox regression model explained 31% of the variance of mortality.Conclusion: a low fat-free mass index is an independent risk factor of mortality in elderly subjects, healthy at the time of body composition measurement. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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