Diagnosis of autism spectrum disorders in 2-year-olds: a study of community practice.

Background: Longitudinal research studies have demonstrated that experienced clinicians using standardized assessment measures can make a reliable diagnosis of autism spectrum disorders (ASDs) in children under age 3. Limited data are available regarding the sensitivity and specificity of these mea...

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Publicado en:Journal of Child Psychology & Psychiatry Vol. 54; no. 2; pp. 178 - 186
Autores principales: Corsello, Christina M., Akshoomoff, Natacha, Stahmer, Aubyn C.
Formato: Artículo
Publicado: Wiley-Blackwell Feb2013
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2013
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      pub: Wiley-Blackwell
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        10.1111/j.1469-7610.2012.02607.x
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        atl: Diagnosis of autism spectrum disorders in 2-year-olds: a study of community practice.
      aug:
        au:
          Corsello, Christina M.
          Akshoomoff, Natacha
          Stahmer, Aubyn C.
        affil:
          Rady Children’s Hospital San Diego, San Diego, CA
          University of California, San Diego, CA, USA
      su:
        California
        Autism
        Diagnosis of autism
        Community health services
        Parent attitudes
        Children
        Chi-squared test
        Discriminant analysis
        Infant development
        Questionnaires
        Research funding
        Scales (Weighing instruments)
        Decision making in clinical medicine
        Research methodology evaluation
        Classification
      sug:
        subj:
          Autism
          Diagnosis of autism
          Community health services
          Parent attitudes
          Children
          California
          Other Individual and Family Services
          Residential Mental Health and Substance Abuse Facilities
          All Other Outpatient Care Centers
          Community health centres
          Other local, municipal and regional public administration
          Scale and Balance Manufacturing
          All other general-purpose machinery manufacturing
          Chi-squared test
          Discriminant analysis
          Infant development
          Questionnaires
          Research funding
          Scales (Weighing instruments)
          Decision making in clinical medicine
          Research methodology evaluation
          Classification
      keyword:
        diagnosis
        services research
        diagnosis
        services research
      ab: Background: Longitudinal research studies have demonstrated that experienced clinicians using standardized assessment measures can make a reliable diagnosis of autism spectrum disorders (ASDs) in children under age 3. Limited data are available regarding the sensitivity and specificity of these measures in community settings. The aims of this study were to determine how well a standardized diagnostic observational measure (Autism Diagnostic Observation Schedule - ADOS) functions alone, and with a brief parent measure within a community setting when administered by community clinicians. Methods: Clinical records for 138 children between the ages of 24 and 36 months of age who were evaluated for possible ASD or social/language concerns at a hospital-based developmental evaluation clinic were examined. Evaluations were conducted by community-based clinical psychologists. Classification results obtained from standardized diagnostic measures were compared with case reviewer diagnosis, by reviewers blind to scores on diagnostic measures, using The Records-based Methodology for ASD Case Definition that was developed by the Metropolitan Atlanta Developmental Disabilities Surveillance Program. Results: When compared with case review diagnosis, the ADOS demonstrated strong sensitivity and specificity for both Autism versus Not Autism and ASD versus Nonspectrum (NS) diagnoses in this young sample. The Social Communication Questionnaire (SCQ), using the lower cutoff of ≥12, had adequate sensitivity when differentiating Autism from Not Autism, but weak sensitivity when differentiating ASD from NS, missing about 80% of the children with pervasive developmental disorder - not otherwise specified. Using either the Modified Checklist for Autism in Toddlers or the SCQ in combination with the ADOS did not result in improved specificity over the ADOS alone and led to a drop in sensitivity when differentiating ASD from NS disorders. Conclusions: These results demonstrate that following best practice guidelines, the ADOS can be successfully incorporated into clinical practice with relatively good sensitivity and specificity, and worked well with a referred sample of 2-year-olds. A parent questionnaire did not lead to any improvement in diagnostic classification above the ADOS used in isolation.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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