Bioassay-guided isolation of urease and α-chymotrypsin inhibitory constituents from the stems of Lawsonia alba Lam. (Henna)
Abstract: Seven constituents were isolated from the stems of Lawsonia alba Lam., following an activity-guided isolation, which include two new constituents, namely lawsorosemarinol (1) and lawsofructose (2), one known compound 2-(β-d-glucopyranosyloxy)-1, 4-naphthoquinone (3) and four compounds, 4-h...
| Publicado en: | Fitoterapia Vol. 84; no. 1; pp. 202 - 208 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
Jan2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=85279588&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 85279588 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0367326X JF4 jtl: Fitoterapia issn: 0367326X maglogo: N pubinfo: dt: Jan2013 vid: 84 iid: 1 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 85279588 104309414 104309414 10.1016/j.fitote.2012.10.007 85279588 ppf: 202 ppct: 6 formats: tig: atl: Bioassay-guided isolation of urease and α-chymotrypsin inhibitory constituents from the stems of Lawsonia alba Lam. (Henna) aug: au: Uddin, Nizam Siddiqui, Bina Shaheen Begum, Sabira Ali, Muhammad Imran Marasini, Bishnu P. Khan, Ajmal Choudhary, M. Iqbal affil: H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan sug: subj: Plants, Medicinal Plant Stems Plant Extracts Analysis Plant Extracts Pharmacodynamics Enzyme Inhibitors Pharmacodynamics Alternative Therapies In Vitro Studies Models, Biological Descriptive Statistics Spectrum Analysis ab: Abstract: Seven constituents were isolated from the stems of Lawsonia alba Lam., following an activity-guided isolation, which include two new constituents, namely lawsorosemarinol (1) and lawsofructose (2), one known compound 2-(β-d-glucopyranosyloxy)-1, 4-naphthoquinone (3) and four compounds, 4-hydroxy coumarine (4), 3-(4-hyroxyphenyl)-triacontyl-(Z)-propenoate (5), 3-(4-hydroxy-3-methoxyphenyl)-triacontyl-(Z)-propenoate (6) and 7-hydroxy-4-methyl coumarin (7) first time isolated from Lawsonia alba. Their structure elucidation was based on spectroscopic data analyses. Compounds 3 and 7 showed a moderate inhibition of urease activity, while rest of them showed less than 50% inhibition. These compounds did not show any significant inhibition against α-chymotrypsin. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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