Optical Coherence Tomography for Rapid Tissue Screening and Directed Histological Sectioning.
In pathology, histological examination of the tissue is the 'gold standard' to diagnose various diseases. It has contributed significantly toward identifying the abnormalities in tissues and cells, but has inherent drawbacks when used for fast and accurate diagnosis. These limitations include the la...
| Publicado en: | Studies in Health Technology & Informatics Vol. 185; pp. 109 - 129 |
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| Autores principales: | , |
| Formato: | diagnostic images pictorial review tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=86380823&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 86380823 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09269630 U1V jtl: Studies in Health Technology & Informatics issn: 09269630 maglogo: N pubinfo: dt: 2013 vid: 185 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 86380823 86380823 104260342 86380823 ppf: 109 ppct: 20 formats: tig: atl: Optical Coherence Tomography for Rapid Tissue Screening and Directed Histological Sectioning. aug: au: Jung, Woonggyu Boppart, Stephen A. affil: Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA sug: subj: Tomography Methods Histology Pathology, Clinical Equipment Design Diagnosis, Eye Biopsy Methods Tomography Utilization Intraoperative Period Lumpectomy Methods ab: In pathology, histological examination of the tissue is the 'gold standard' to diagnose various diseases. It has contributed significantly toward identifying the abnormalities in tissues and cells, but has inherent drawbacks when used for fast and accurate diagnosis. These limitations include the lack of in vivo observation in real time and sampling errors due to limited number and area coverage of tissue sections. Its diagnostic yield also varies depending on the ability of the physician and the effectiveness of any image guidance technique that may be used for tissue screening during excisional biopsy. In order to overcome these current limitations of histology-based diagnostics, there are significant needs for either complementary or alternative imaging techniques which perform non-destructive, high resolution, and rapid tissue screening. Optical coherence tomography (OCT) is an emerging imaging modality which allows real-time cross-sectional imaging with high resolutions that approach those of histology. OCT could be a very promising technique which has the potential to be used as an adjunct to histological tissue observation when it is not practical to take specimens for histological processing, when large areas of tissue need investigating, or when rapid microscopic imaging is needed. This review will describe the use of OCT as an image guidance tool for fast tissue screening and directed histological tissue sectioning in pathology. pubtype: Academic Journal doctype: diagnostic images pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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