A Theoretical Investigation on the Mechanism and Stereochemical Course of the Addition of (E)-2-Butenyltrimethylsilane to Acetaldehyde by Electrophilic and Nucleophilic Activation.

The diastereoselectivity of the addition of (E)-2-butenyltrimethylsilane to acetaldehyde under electrophilic (BF, HO) and nucleophilic (F-) activation is investigated using density functional theory (M06-2X). The interaction-distortion/activation-strain model of reactivity is used to rationalize the...

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Publicado en:	Journal of the American Chemical Society Vol. 135; no. 12; pp. 4743 - 4757
Autores principales:	Wolf, Larry M., Denmark, Scott E.
Formato:	Artículo
Publicado:	American Chemical Society 3/27/2013
Materias:	Density functionals Acetaldehyde Electrophilic substitution reactions Electrophilic addition reactions Nucleophilic reactions Nucleophilic addition (Chemistry)
Acceso en línea:	Ver este registro en EBSCOhost