EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma.

Purpose: More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1 genes, due to the t(11;22)(q24;q12) translocation. At the molecular level, the EWS-FLI1 rearrangements show great diversity. Specifically, many different combinations of exons from EWS and FLI1 encode in-frame fusio...

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Publicado en:	Journal of Clinical Oncology Vol. 16; no. 4; pp. 1248 - 1256
Autores principales:	de Alava, Enrique, Kawai, Akira, Healey, John H., Fligman, Igal, Meyers, Paul A., Huvos, Andrew G., Gerald, William L., Jhanwar, Suresh C., Argani, Pedram, Antonescu, Cristina R., Pardo-Mindan, F. Javier, Ginsberg, Jill, Womer, Richard, Lawlor, Elizabeth R., Wunder, Jay, Andrulis, Irene, Sorensen, Poul H. B., Barr, Frederic G., Ladanyi, Marc, de Alava, E
Formato:	research Journal Article
Publicado:	American Society of Clinical Oncology Apr1998
Acceso en línea:	Ver este registro en EBSCOhost