The nutritional status of patients with tuberculosis in comparison with tuberculosis-free contacts in Delft, Western Cape.
Objective: To report on the nutritional status of newly diagnosed patients with pulmonary tuberculosis in comparison to contacts who are tuberculosis free. Design: This was a community-based case-control study. Setting and subjects: The study was conducted in Delft, a periurban community in the West...
| Publicado en: | South African Journal of Clinical Nutrition Vol. 25; no. 4; pp. 180 - 186 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=88923868&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 88923868 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16070658 39WI jtl: South African Journal of Clinical Nutrition issn: 16070658 maglogo: N pubinfo: dt: 2012 vid: 25 iid: 4 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 88923868 104192609 104192609 10.1080/16070658.2012.11734425 88923868 ppf: 180 ppct: 6 formats: fmt: @attributes: type: P tig: atl: The nutritional status of patients with tuberculosis in comparison with tuberculosis-free contacts in Delft, Western Cape. aug: au: Lombardo, C. C. Swart, R. Visser, M. E. affil: Lecturer, University of the Western Cape sug: subj: Nutritional Assessment In Adulthood Malnutrition Complications Tuberculosis, Pulmonary Complications Human Funding Source Comparative Studies South Africa Matched Case Control Questionnaires Interviews Body Weights and Measures Descriptive Statistics Confidence Intervals Odds Ratio Adolescence Young Adult Adult Middle Age Aged Tuberculosis, Pulmonary Diagnosis Nutritional Assessment Methods Data Analysis Software T-Tests Mann-Whitney U Test Chi Square Test Male Female Micronutrients Analysis Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objective: To report on the nutritional status of newly diagnosed patients with pulmonary tuberculosis in comparison to contacts who are tuberculosis free. Design: This was a community-based case-control study. Setting and subjects: The study was conducted in Delft, a periurban community in the Western Cape. Forty-three newly diagnosed patients with tuberculosis were recruited as cases and matched according to age, gender and race to 43 tuberculosis-free contacts. Outcome measures: Each participant was interviewed and completed a structured questionnaire to provide demographic information. Weight was measured to the nearest 0.1 kg and height to the nearest 1 mm. Mid-upper-arm circumference (MUAC) was measured to the nearest 1 mm and skinfold thickness measurements to the nearest 0.2 mm. The 24-hour dietary recall method was used to obtain dietary information and analysed in the nutrition database of the Medical Research Council in order to translate foods into nutrients. Biochemical analyses were carried out to measure concentrations of transferrin, albumin, C-reactive protein (CRP), ferritin, zinc, copper and vitamins A and E. Means (± standard deviation) and confidence intervals were used to describe serum micronutrient and biochemical levels. Medians (minimum and maximum) were used to describe the nutrient intake and anthropometric status of patients. Results: The median body mass index for tuberculosis cases was 18.80 kg/m² [interquartile range (IQR) 14.35, 32.11] and for tuberculosisfree contacts 21.17 kg/m² (IQR 16.75, 34.98), with a significant difference between the groups with a p-value = 0.001. There was a statistically significant difference in weight (p-value = 0.002) and MUAC (p-value = 0.000) between groups; and in ferritin (p-value = 0.000) and CRP (p-value = 0.000) in patients with tuberculosis; while albumin (p-value = 0.000), serum zinc (p-value = 0.000) and serum vitamin A (p-value = 0.000) were significantly lower in cases. Conclusion: Newly diagnosed patients with tuberculosis have a poorer nutritional status than their tuberculosis-free counterparts. This may be a result of the acute phase response, increased metabolism and anorexia. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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