Síntesis y análisis de la biocompatibilidad y osteoconductividad de un composito hidroxiapatita/colágeno, implantado en el sacro de un perro.
A new material was synthetized using the wet precipitation method to obtain an osseous insert that can be used in medical applications. A solution of CaCl 198 mM and another one with 119 mM of (NH)HPO dissolved in distilled water were simultaneously prepared with the slowly and continuous addition o...
| Publicado en: | Revista Mexicana de Ingeniería Biomédica Vol. 32; no. 2; pp. 119 - 125 |
|---|---|
| Autores principales: | , , , , |
| Formato: | Artículo |
| Publicado: |
Sociedad Mexicana de Ingenieria Biomedica, A.C.
dic2011
|
| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=88950424&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 88950424 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 01889532 7L3 jtl: Revista Mexicana de Ingeniería Biomédica issn: 01889532 maglogo: N pubinfo: dt: dic2011 vid: 32 iid: 2 pid: 20850 pub: Sociedad Mexicana de Ingenieria Biomedica, A.C. artinfo: ui: 88950424 ppf: 119 ppct: 6 formats: fmt: @attributes: type: P size: 180KB tig: atl: Síntesis y análisis de la biocompatibilidad y osteoconductividad de un composito hidroxiapatita/colágeno, implantado en el sacro de un perro. aug: au: Martínez Ramírez, Enrique Quiroz Garcés, Alejandro Velasco Villareal, René de la Rosa Orea, Guillermo González Pérez, Manuel affil: Postgrado en Ingeniería Biomédica, UPAEP Clínica Veterinaria la Paz su: Hydroxyapatite Distilled water Fourier transforms Biocompatibility Collagen sug: subj: Hydroxyapatite Distilled water Fourier transforms Biocompatibility Collagen keyword: collagen osteon insert colágeno Hidroxiapatita injerto óseo ab: A new material was synthetized using the wet precipitation method to obtain an osseous insert that can be used in medical applications. A solution of CaCl 198 mM and another one with 119 mM of (NH)HPO dissolved in distilled water were simultaneously prepared with the slowly and continuous addition of NHOH dissolved in water . Finally, 3 ml of collagen was aggregated to the solution. The precipitated was washed out several times with distilled wáter, filtered and dried in an incubator at 40°C. The samples were characterized by X-ray diffraction, surface electronic microscopy, Fourier transformation based infrared spectroscopy. Three different cubes composites with the volume of 10 x 10 x 10 mm3 each one were prepared and implanted into the dtygre sacrum of a female dog to check the osseous integration and the biocompatibility of the new material. Histological and radiographic studies were developed showed the development of osseous callus and the consequent formation of new bone section. Se sintetizó un nuevo biomaterial mediante el método de precipitación húmeda con el fin de obtener un injerto óseo capaz de utilizarse en aplicaciones médicas. Se preparó una solución de CaCl198 mM y una solución 119 mM de (NH)HPO con agua destilada; ambas soluciones se mezclaron simultáneamente mientras que una solución de NHOH era agregada lentamente mediante goteo, finalmente se agregaron 3 ml de colágeno. El precipitado obtenido fue lavado varias veces con agua destilada, filtrado y secado en una incubadora a 40 C. Las muestras fueron caracterizadas mediante difracción de rayos x (DRX), microscopia electrónica de barrido (SEM), espectroscopia de infrarrojo por transformadas de Fourier (FTIR). Se prepararon tres cubos de composito de 10 x 10 x 10 mm³ cada uno, y fueron implantados en el sacro de un perro hembra para comprobar osteointegración y biocompatibilidad, se realizaron estudios histológicos y radiográficos que mostraron el desarrollo de un callo óseo y la formación de hueso nuevo. pubtype: Academic Journal doctype: Article src: R language: Spanish refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista Mexicana de Ingeniería Biomédica is the property of Sociedad Mexicana de Ingenieria Biomedica, A.C. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista Mexicana de Ingeniería Biomédica holder: Sociedad Mexicana de Ingenieria Biomedica, A.C. dt: @attributes: year: 2011 holdings: @attributes: islocal: N |
|---|