Beyond Surveillance: A Role for Respondent-driven Sampling in Implementation Science.

We are now in the fourth decade of the human immunodeficiency virus (HIV) pandemic. Several novel prevention tools have been identified, and prevalence and incidence have declined in many settings. A remaining challenge is the delivery of preventive interventions to hard-to-reach populations, includ...

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Published in:American Journal of Epidemiology Vol. 178; no. 2; pp. 260 - 268
Main Authors: Solomon, Sunil S., Lucas, Gregory M., Celentano, David D., Sifakis, Frangiscos, Mehta, Shruti H.
Format: research tables/charts Journal Article
Published: Oxford University Press / USA Aug2013
Online Access:View this record in EBSCOhost
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      dt: Aug2013
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      pub: Oxford University Press / USA
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        atl: Beyond Surveillance: A Role for Respondent-driven Sampling in Implementation Science.
      aug:
        au:
          Solomon, Sunil S.
          Lucas, Gregory M.
          Celentano, David D.
          Sifakis, Frangiscos
          Mehta, Shruti H.
      sug:
        subj:
          Disease Surveillance
          HIV Infections Prevention and Control
          Risk Taking Behavior
          Research Subject Recruitment Methods
          Human
          Funding Source
          Counseling
          Gay Persons India
          AIDS Serodiagnosis
          Referral and Consultation Methods
          Cluster Analysis Methods
          Social Networks
          Peer Group
          Random Sample Methods
          India
          Hypothesis
          Epidemiological Research Methods
      ab: We are now in the fourth decade of the human immunodeficiency virus (HIV) pandemic. Several novel prevention tools have been identified, and prevalence and incidence have declined in many settings. A remaining challenge is the delivery of preventive interventions to hard-to-reach populations, including men who have sex with men and injection drug users. Leaders in the field of HIV have called for a new focus on implementation science, which requires a shift in thinking from individual randomized controlled trials to cluster-randomized trials. Multiple challenges need to be addressed in the conduct of cluster-randomized trials, including: 1) generalizability of the study population to the target population, 2) potential contamination through overlap/exchange of members of control and intervention clusters, and 3) evaluation of effectiveness at multiple levels of influence. To address these key challenges, we propose a novel application of respondent-driven sampling—a chain-referral strategy commonly used for surveillance—in the recruitment of participants for the evaluation of a cluster-randomized trial of a community intervention. We illustrate this application with an empirical example of a cluster-randomized trial that is currently under way to assess the effectiveness of men's wellness centers in improving utilization of HIV counseling and testing among men who have sex with men in India.
      pubtype: Academic Journal
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    language: English
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