In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study.
Elasticity imaging methods have been used to study kidney mechanical properties and have demonstrated that the kidney elastic modulus increases with disease state. However, studies in swine suggest that kidney elastic modulus is also affected by hemodynamic variables. A newly emerging method called...
| Publicado en: | Biomedical Engineering Journal / Revista Ingeniería Biomédica Vol. 7; no. 13; pp. 68 - 79 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
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Biomedical Engineering Journal / Revista Ingenieria Biomedica
ene-jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=89920417&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 89920417 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 19099762 EUJC jtl: Biomedical Engineering Journal / Revista Ingeniería Biomédica issn: 19099762 maglogo: N pubinfo: dt: ene-jun2013 vid: 7 iid: 13 pid: 85465 pub: Biomedical Engineering Journal / Revista Ingenieria Biomedica artinfo: ui: 89920417 ppf: 68 ppct: 11 formats: fmt: @attributes: type: P size: 1.3MB tig: atl: In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study. aug: au: Amador, Carolina Urban, Matthew Kinnick, Randall Shigao Chen Greenleaf, James F. affil: Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, United States su: Blood flow Laboratory swine Viscoelasticity Elasticity Acute kidney failure Viscosity sug: subj: Blood flow Laboratory swine Viscoelasticity Elasticity Acute kidney failure Viscosity keyword: elasticity medical imaging Renal cortex ultrasound viscosity Corteza renal elasticidad imágenes médicas ultrasonido viscosidad ab: Elasticity imaging methods have been used to study kidney mechanical properties and have demonstrated that the kidney elastic modulus increases with disease state. However, studies in swine suggest that kidney elastic modulus is also affected by hemodynamic variables. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV) offers a tool to determine renal elasticity and viscosity in vivo. The purpose of this study was directed toward evaluating the feasibility of SDUV for in vivo measurements of healthy swine kidney during acute gradual decease of renal blood flow. In this study in vivo SDUV measurements were made on a group of 5 normal swine kidneys at baseline renal blood flow (RBF) and 25, 50, 75 and 100% decrease in RBF. The shear elastic modulus at full baseline was 7.04 ± 0.92 kPa and 3.48 ± 0.20 kPa at 100% decrease in RBF. The viscosity did not change between baseline (2.23 ± 0.33 Pa·s) and 100% decrease in RBF (2.03 ± 0.32 Pa·s). The data from this study indicates that other variables such as local blood flow, pressure and volume as well as method accuracy need to be measured to illustrate the relationship between shear elasticity and viscosity associated with acute kidney processes. Métodos de imágenes de elasticidad se han utilizado para estudiar las propiedades mecánicas renales y han demostrado que el módulo elástico de los riñones del aumenta con el estado de enfermedades renales. Sin embargo, estudios en cerdos sugieren que el riñón módulo elástico también se ve afectada por las variables hemodinámicas. Un método emergente llamado Shearwave Dispersion Ultrasound Vibrometry (SDUV) ofrece una herramienta para determinar la elasticidad y la viscosidad renal. El propósito de este estudio se dirige a la evaluación de la viabilidad de SDUV para mediciones las propiedades viscoelasticas del riñón saludable durante variación aguda del flujo sanguíneo renal. En este estudio el método SDUV se realizó en un grupo de 5 riñones porcinos normales al inicio del flujo sanguíneo renal (RBF) basal y 25, 50, 75 y 100% de disminución en el RBF. El módulo elástico basal fue de 7,04 ± 0,92 kPa y 3,48 ± 0,20 kPa a 100% de disminución del RBF. La viscosidad no cambió entre el momento basal (2,23 ± 0,33 Pa ·s) y el 100% de disminución del RBF (2,03 ± 0,32 Pa ·s). Los datos de este estudio indican que variables tales como el flujo local de sangre, la presión y el volumen así como el método exactitud deben ser medidos para ilustrar la relación entre la elasticidad y la viscosidad asociada con los procesos renales agudos. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Biomedical Engineering Journal / Revista Ingeniería Biomédica is the property of Biomedical Engineering Journal / Revista Ingenieria Biomedica and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Biomedical Engineering Journal / Revista Ingeniería Biomédica holder: Biomedical Engineering Journal / Revista Ingenieria Biomedica dt: @attributes: year: 2013 holdings: @attributes: islocal: N |
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