Risk factors for aseptic loosening of Müller-type straight stems.

Background and purpose Even small differences in design variables for the femoral stem may influence the outcome of a hip arthroplasty. We performed a risk factor analysis for aseptic loosening of 4 different versions of cemented Müller-type straight stems with special emphasis on design modificatio...

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Publicado en:Acta Orthopaedica Vol. 84; no. 4; pp. 353 - 360
Autores principales: Clauss, Martin, Gersbach, Silke, Butscher, Andre, Ilchmann, Thomas
Formato: pictorial research tables/charts Journal Article
Publicado: Medical Journals Sweden AB Aug2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Medical Journals Sweden AB
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        atl: Risk factors for aseptic loosening of Müller-type straight stems.
      aug:
        au:
          Clauss, Martin
          Gersbach, Silke
          Butscher, Andre
          Ilchmann, Thomas
        affil: Clinic for Orthopedic and Trauma Surgery, Kantonsspital Baselland Liestal
      sug:
        subj:
          Arthroplasty, Replacement, Hip Methods
          Joint Prosthesis Statistics and Numerical Data
          Prosthesis Design Statistics and Numerical Data
          Prosthesis Failure
          Human
          Arthroplasty, Replacement, Hip Adverse Effects
          Arthroplasty, Replacement, Hip Equipment and Supplies
          Prospective Studies
          Male
          Female
          Registries, Disease
          Risk Assessment
          Risk Factors
          Treatment Outcomes
          Cox Proportional Hazards Model
          Regression
          Confidence Intervals
          Relative Risk
          Survival Analysis
          Kaplan-Meier Estimator
          Log-Rank Test
          Data Analysis Software
          Descriptive Statistics
          Aged
          Aged: 65+ years
          Male
          Female
      ab: Background and purpose Even small differences in design variables for the femoral stem may influence the outcome of a hip arthroplasty. We performed a risk factor analysis for aseptic loosening of 4 different versions of cemented Müller-type straight stems with special emphasis on design modifications (2 shapes, MSS or SL, and 2 materials, CoNiCrMo (Co) or Ti-6Al-7Nb (Ti)). Methods We investigated 828 total hip replacements, which were followed prospectively in our in-house register. All stems were operated in the same setup, using Sulfix-6 bone cement and a second-generation cementing technique. Demographic and design-specific risk factors were analyzed using an adjusted Cox regression model. Results The 4 versions showed marked differences in 15-year stem survival with aseptic loosening as the endpoint: 94% (95% CI: 89-99) for MSS Co, 83% (CI: 75-91) for SL Co, 81% (CI: 76-87) for MSS Ti and 63% (CI: 56-71) for SL Ti. Cox regression analysis showed a relative risk (RR) for aseptic loosening of 3 (CI: 2-5) for stems made of Ti and of 2 (CI: 1-2) for the SL design. The RR for aseptic stem loosening increased to 8 (CI: 4-15) when comparing the most and the least successful designs (MSS Co and SL Ti). Interpretation Cemented Müller-type straight stems should be MSS-shaped and made of a material with high flexural strength (e.g. cobalt-chrome). The surface finish should be polished (Ra < 0.4 µm). These technical aspects combined with modern cementing techniques would improve the survival of Müller-type straight stems. This may be true for all types of cemented stems.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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