Factors Affecting Sputum Conversion Time in Patients with Smear-Positive Tuberculosis.
Objective: To determine the possible factors affecting the sputum conversion time in patients with sputum smear-positive tuberculosis. Material and Methods: Files of 163 smear positive lung tuberculosis patients who had been treated at the Umraniye Tuberculosis Dispensary in 2006 were retrospectivel...
| Publicado en: | Turkiye Klinikleri Archives of Lung Vol. 14; no. 2; pp. 39 - 46 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Turkiye Klinikleri
2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=90803442&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 90803442 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13090119 BE7H jtl: Turkiye Klinikleri Archives of Lung issn: 13090119 maglogo: N pubinfo: dt: 2013 vid: 14 iid: 2 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 90803442 90803442 104145495 90803442 ppf: 39 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Factors Affecting Sputum Conversion Time in Patients with Smear-Positive Tuberculosis. aug: au: DURMUŞ, Nagihan SOLAKOĞLU UÇAR, Mine ÖZTÜRK, Filiz POLAT, Dilek TORUN, Elif affil: Clinic of Chest Diseases, Ümraniye Tuberculosis Dispensary, Marmara University Faculty of Medicine, İstanbul sug: subj: Tuberculosis Diagnosis Sputum Analysis Lung Diseases Physiopathology Human Patient Assessment Data Analysis Pearson's Correlation Coefficient Mann-Whitney U Test Adult Male Female Radiography, Thoracic Medical Organizations Body Mass Index Evaluation Drug Resistance, Microbial Adult: 19-44 years Male Female ab: Objective: To determine the possible factors affecting the sputum conversion time in patients with sputum smear-positive tuberculosis. Material and Methods: Files of 163 smear positive lung tuberculosis patients who had been treated at the Umraniye Tuberculosis Dispensary in 2006 were retrospectively examined. A p value of <0.05 was considered significant for the statistical analyses. Pearson Chi-Square test was applied for the cathegorical variables and the frequency analyses. The Mann Whitney-U Test was used for variables without a normal distribution. Results: The age of patients ranged between 16 and 70 years (mean: 33.6±13.3 years); 124 (76.1%) of the patients were male and 39 (23.9%) of were female. The conversion time was 2 months or shorter in 127 (77.9%) patients (mean conversion time: 1.96±1.04 months). We found no relationship between the conversion time and gender, smoking status, hospitalization, comorbidity and extent of radiological findings. The conversion time was 3 months or longer in 28 (31.8%) of 88 patients who displayed a cavity on chest X-ray and in 8 (10.8%) of 74 patients who displayed no cavity. This was statistically significant (p=0.001). The median value of the body mass index was determined as 21.4 kg/m2 (interquartile range:19.2-22.9) in patients in whom the conversion time was 2 months or shorter, and 19.6 kg/m2 (interquartile range:18.1-20.9) in patients in whom the conversion time was 3 months or longer. This result was statistically significant (p=0.015). Conclusion: The presence of a cavity on chest X-ray and low body mass index are factors that increasing time of sputum smear conversion. Amaç: Yayma-pozitif akciğer tüberkülozu hastalarında balgamda konversiyon süresini etkileyen olası faktörleri belirlemek. Gereç ve Yöntemler: 2006 yılında Ümraniye Verem Savaş Dis panserinde tedavi edilen toplam 163 yayma-pozitif akciğer tüberkülozlu hastanın dosyaları geriye dönük olarak incelendi. İstatistiksel analizler için p<0,05 anlamlı kabul edildi. Kategorik değişkenler ve sıklık analizleri için Pearson ki-kare testi uygulandı. Normal dağılım göstermeyen değişkenler için Mann Whitney-U testi kullanıldı. Bulgular: Yaşları 16 ile 70 yıl arasında (ortalama: 33,6±13,3 yıl) değişen hastaların, 124 (%76,1)’ü erkek, 39 (%23,9)’u kadın olup, 127 (%77,9) hastada konversiyon süresi 2 ay ve altında idi (ortalama konversiyon süresi 1,96±1,04 ay). Konversiyon süresi ile cinsiyet, sigara içme durumu, hastanede yatış, komorbidite varlığı ve radyolojik bulguların yaygınlığı arasında ilişki saptamadık. Akciğer grafisinde kavite olan 88 hastanın 28 (%31,8)'inde, kavite ol mayan 74 hastanın ise 8 (%10,8)’inde konversiyon süresi 3 ay ve üstünde olup, bu durum istatistiksel olarak anlamlı bulundu (p=0,001). Konversiyon süresi 2 ay ve altında olan hastalarda vücut kitle indeksi ortanca değeri 21,4 kg/m2 (%25-19,2/%75-22,9) iken, 3 ay ve üstünde olan hastalarda ise 19,6 kg/m2 (%25-18,1/%75-20,9) saptandı, bu sonuç istatistiksel olarak anlamlı idi (p=0,015). Sonuç: Akciğer grafisinde kavite varlığı ve düşük vücut kitle indeks değeri, balgamda konversiyon süresini uzatan faktörlerdir. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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