CT Radiation Dose and Image Quality Optimization Using a Porcine Model.

Purpose To evaluate potential radiation dose savings and resultant image quality effects with regard to optimization of commonly performed computed tomography (CT) studies derived from imaging a porcine (pig) model. Methods Imaging protocols for 4 clinical CT suites were developed based on the lowes...

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Publicado en:Radiologic Technology Vol. 85; no. 2; pp. 127 - 137
Autores principales: Zarb, Francis, McEntee, Mark F., Rainford, Louise
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: American Society of Radiologic Technologists Nov/Dec2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov/Dec2013
      vid: 85
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      pub: American Society of Radiologic Technologists
      place: Alburquerque, New Mexico
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        atl: CT Radiation Dose and Image Quality Optimization Using a Porcine Model.
      aug:
        au:
          Zarb, Francis
          McEntee, Mark F.
          Rainford, Louise
        affil: Lecturer, Department of Radiography, Faculty of Health Sciences, University of Malta
      sug:
        subj:
          Radiation Dosage Methods
          Tomography, X-Ray Computed Methods
          Models, Anatomic
          Protocols
          Animal Studies
          Swine
          Phantoms, Imaging
          Radiation, Ionizing
          Mediterranean Islands
          Surveys
          Questionnaires
          Radiology Service
          Regression
          P-Value
          Descriptive Statistics
          Summated Rating Scaling
          Scales
          Data Analysis Software
          Confidence Intervals
          Kruskal-Wallis Test
          Mann-Whitney U Test
          kappa Statistic
          Head Radiation Effects
          Abdomen Radiation Effects
          Thorax Radiation Effects
      ab: Purpose To evaluate potential radiation dose savings and resultant image quality effects with regard to optimization of commonly performed computed tomography (CT) studies derived from imaging a porcine (pig) model. Methods Imaging protocols for 4 clinical CT suites were developed based on the lowest milliamperage and kilovoltage, the highest pitch that could be set from current imaging protocol parameters, or both. This occurred before significant changes in noise, contrast, and spatial resolution were measured objectively on images produced from a quality assurance CT phantom. The current and derived phantom protocols were then applied to scan a porcine model for head, abdomen, and chest CT studies. Further optimized protocols were developed based on the same methodology as in the phantom study. The optimization achieved with respect to radiation dose and image quality was evaluated following data collection of radiation dose recordings and image quality review. Relative visual grading analysis of image quality criteria adapted from the European guidelines on radiology quality criteria for CT were used for studies completed with both the phantom-based or porcine-derived imaging protocols. Results In 5 out of 16 experimental combinations, the current clinical protocol was maintained. In 2 instances, the phantom protocol reduced radiation dose by 19% to 38%. In the remaining 9 instances, the optimization based on the porcine model further reduced radiation dose by 17% to 38%. Conclusion The porcine model closely reflects anatomical structures in humans, allowing the grading of anatomical criteria as part of image quality review without radiation risks to human subjects. This study demonstrates that using a porcine model to evaluate CT optimization resulted in more radiation dose reduction than when imaging protocols were tested solely on quality assurance phantoms.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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