Screening for depression in Parkinson's disease: the performance of two screening questions.
Background: the study objective was to evaluate the validity of the two questions recommended by the UK. National Institute for Health and Clinical Excellence for depression screening in Parkinson's disease (PD).Methods: one hundred and twenty patients attending a PD out-patient clinic were intervie...
| Publicado en: | Age & Ageing Vol. 43; no. 2; pp. 200 - 206 |
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| Autores principales: | , , , |
| Formato: | Artículo |
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Oxford University Press / USA
Mar2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=94516174&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 94516174 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Mar2014 vid: 43 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 94516174 10.1093/ageing/aft152 ppf: 200 ppct: 6 formats: tig: atl: Screening for depression in Parkinson's disease: the performance of two screening questions. aug: au: Baillon, Sarah Dennis, Michael Lo, Nelson Lindesay, James affil: Department of Health Sciences , University of Leicester , Leicester, Leics , UK College of Medicine , Swansea University , Swansea, Wales , UK Department of Geriatric Medicine , University Hospitals of Leicester NHS Trust , Leicester, Leics , UK su: Diagnosis of mental depression Epidemiology Interviewing Psychological tests Old age Psychology Parkinson's disease Confidence intervals Neuropsychological tests Research methodology Data analysis Descriptive statistics sug: subj: Diagnosis of mental depression Epidemiology Interviewing Psychological tests Old age Psychology Parkinson's disease Confidence intervals Neuropsychological tests Research methodology Data analysis Descriptive statistics keyword: depression Geriatric Depression Scale older people screening depression Geriatric Depression Scale older people screening ab: Background: the study objective was to evaluate the validity of the two questions recommended by the UK. National Institute for Health and Clinical Excellence for depression screening in Parkinson's disease (PD).Methods: one hundred and twenty patients attending a PD out-patient clinic were interviewed in a standardised manner using relevant sections of the Present State Examination- Schedules for Clinical Assessment in Neuropsychiatry to identify depression according to Diagnostic and Statistical Manual (4th edition) criteria. Participants then completed the two depression screening questions and the 15-item Geriatric Depression Scale (GDS-15).Results: sensitivity, specificity, positive and negative predictive values of the two questions and GDS-15 for major and minor depression combined were calculated for different cut-off scores and a receiver operating characteristics (ROC) analysis was conducted. A threshold of one or more positive responses to the two screening questions gave a sensitivity of 100% and specificity of 84% (positive predictive value 54%, negative predictive value 100%). The area under the ROC curve was 0.95. The optimal cut-off for the GDS-15 was 5/6, which gave a sensitivity of 84% and specificity of 89% (positive predictive value 59%, negative predictive value 97%), and the area under the curve was 0.92.Conclusion: this study shows that the two depression screening questions can be used as an initial screen for depression in patients with PD who have no significant cognitive impairment. A positive response to either of the questions would indicate that further diagnostic assessment may be warranted. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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