Endometrial Carcinoma in Women Aged 40 Years and Younger.
Context.-Endometrial carcinoma is a disease of older postmenopausal women, and is relatively uncommon in patients younger than 40 years. Endometrial carcinomas in this age group may be familial, associated with Lynch syndrome, or sporadic. Objectives.-To present our current knowledge of endometrial...
| Publicado en: | Archives of Pathology & Laboratory Medicine Vol. 138; no. 3; pp. 335 - 343 |
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| Autores principales: | , |
| Formato: | pictorial tables/charts Journal Article |
| Publicado: |
College of American Pathologists
Mar2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=94885758&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 94885758 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00039985 1FS jtl: Archives of Pathology & Laboratory Medicine issn: 00039985 maglogo: N pubinfo: dt: Mar2014 vid: 138 iid: 3 pid: 2550 pub: College of American Pathologists place: Northfield, Illinois artinfo: ui: 94885758 104046267 104046267 10.5858/arpa.2012-0654-RA 94885758 ppf: 335 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Endometrial Carcinoma in Women Aged 40 Years and Younger. aug: au: Garg, Karuna Soslow, Robert A. affil: Department of Pathology, University of California San Francisco sug: subj: Endometrial Neoplasms Physiopathology Carcinoma Physiopathology Age Factors Endometrial Neoplasms Pathology Carcinoma Pathology Prognosis Neoplastic Syndromes, Hereditary Endometrial Neoplasms Therapy Carcinoma Therapy Adult Adult: 19-44 years ab: Context.-Endometrial carcinoma is a disease of older postmenopausal women, and is relatively uncommon in patients younger than 40 years. Endometrial carcinomas in this age group may be familial, associated with Lynch syndrome, or sporadic. Objectives.-To present our current knowledge of endometrial carcinomas in women younger than 40 years. Data Sources.-The review is based on previously published articles on this topic. Conclusions.-Most endometrial carcinomas that occur in this age group are associated with estrogen excess. They are usually low-grade endometrioid carcinomas that present at low stages and are associated with favorable clinical outcomes. Tumors associated with mismatch repair abnormalities and Lynch syndrome appear to be distinct, with worse prognostic factors and, possibly, clinical behavior. Conservative hormonal therapy and ovarian conservation are reasonable considerations in the management of these young patients, but carry the risk of tumor progression, recurrence, and an occult synchronous or metachronous ovarian carcinoma. pubtype: Academic Journal doctype: pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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