Comparative urease enzyme inhibition profile of leaves and stems of Rumex nervosus vahl.

Ureases inhibitory agents are becoming important because of their application in treating many aliments. This work describes the urease inhibitory potential of the crude extracts of leaves and stems ofRumex nervosus, which includes crude extracts as well as various sub-fractions,n-hexane, chloroform...

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Publicado en:Natural Product Research Vol. 28; no. 24; pp. 2355 - 2358
Autores principales: Khan, Rasool, Quradha, Mohammed Mansour, Saif, Abdullah Qasem, Ali, Jawad, Rauf, Abdur, Khan, Ajmal
Formato: Journal Article
Publicado: Taylor & Francis Ltd Dec2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2014
      vid: 28
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        10.1080/14786419.2014.940346
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        atl: Comparative urease enzyme inhibition profile of leaves and stems of Rumex nervosus vahl.
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          Khan, Rasool
          Quradha, Mohammed Mansour
          Saif, Abdullah Qasem
          Ali, Jawad
          Rauf, Abdur
          Khan, Ajmal
        affil: Institute of Chemical Sciences, University of Peshawar, Peshawar25120, KPK, Pakistan
      sug:
      ab: Ureases inhibitory agents are becoming important because of their application in treating many aliments. This work describes the urease inhibitory potential of the crude extracts of leaves and stems ofRumex nervosus, which includes crude extracts as well as various sub-fractions,n-hexane, chloroform, ethyl acetate and methanol. The crude extracts of stems and leaves exhibited promising ureases inhibition (IC50values of 17.5 ± 0.84 and 29.6 ± 0.96 μg/mL, respectively). Among the sub-fractions, methanol-soluble fractions of leaves and stems showed significant inhibition having IC50values of 21.9 ± 0.67 and 21.5 ± 0.69 μg/mL, respectively, followed by ethyl acetate fractions of stems and leaves.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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