Bifunctional Porphyrin Catalysts for the Synthesis of Cyclic Carbonates from Epoxides and CO: Structural Optimization and Mechanistic Study.

We prepared bifunctional Mg porphyrin catalysts 1 for the solvent-free synthesis of cyclic carbonates from epoxides and CO. The activities of Id, lh, and li, which have Br , Cl, and I counteranions, respectively, increased in the order li < lh < Id. Catalysts Id and l j—m, which bear four tetraalkyl...

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Publicado en:Journal of the American Chemical Society Vol. 136; no. 43; pp. 15270 - 15280
Autores principales: Tadashi Ema, Yuki Miyazaki, Junta Shimonishi, Chihiro Maeda, Jun-ya Hasegawa
Formato: Artículo
Publicado: American Chemical Society 10/29/2014
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: 10/29/2014
      vid: 136
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      pub: American Chemical Society
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        10.1021/ja507665a
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        atl: Bifunctional Porphyrin Catalysts for the Synthesis of Cyclic Carbonates from Epoxides and CO: Structural Optimization and Mechanistic Study.
      aug:
        au:
          Tadashi Ema
          Yuki Miyazaki
          Junta Shimonishi
          Chihiro Maeda
          Jun-ya Hasegawa
        affil:
          Division of Chemistry and Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Tsushima, Okayama 700-8530, Japan
          Catalysis Research Center, Hokkaido University, Kita 21, Nishi 10, Kita-ku, Sapporo 001-0021, Japan
      su:
        Bifunctional catalysis
        Catalysis
        Porphyrins
        Biological pigments
        Carbonates
      sug:
        subj:
          Bifunctional catalysis
          Catalysis
          Porphyrins
          Biological pigments
          Carbonates
      ab: We prepared bifunctional Mg porphyrin catalysts 1 for the solvent-free synthesis of cyclic carbonates from epoxides and CO. The activities of Id, lh, and li, which have Br , Cl, and I counteranions, respectively, increased in the order li < lh < Id. Catalysts Id and l j—m, which bear four tetraalkylammonium bromide groups with different alkyl chain lengths, showed comparable but slightly different activities. Based on the excellent catalyst Id, we synthesized Mg11 porphyrin lo with eight tetraalkylammonium bromide groups, which showed even higher catalytic activity (turnover number, 138,000; turnover frequency, 19,000 h”1). The catalytic mechanism was studied by using Id. The yields were nearly constant at initial CO pressures in the 1—6 MPa range, suggesting that CO was not involved in the rate-determining step in this pressure range. No reaction proceeded in supercritical CO, probably because the epoxide (into which the catalyst dissolved) dissolved in and was diluted by the supercritical CO. Experiments with lsO-labeled CO and D-labeled epoxide suggested that the catalytic cycle involved initial nucleophilic attack of Br on the less hindered side of the epoxide to generate an oxyanion, which underwent CO insertion to afford a CO2 adduct; subsequent intramolecular ring closure formed the cyclic carbonate and regenerated the catalyst. Density functional theory calculations gave results consistent with the experimental results, revealing that the quaternary ammonium cation underwent conformational changes that stabilized various anionic species generated during the catalytic cycle. The high activity of Id and lo was due to the cooperative action of the Mg and Br and a conformational change (induced-fit) of the quaternary ammonium cation.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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