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Timing Is Everything: Unifying Codon Translation Rates and Nascent Proteome Behavior.

Experiments have demonstrated that changing the rate at which the ribosome translates a codon position in an mRNA molecule's open reading frame can alter the behavior of the newly synthesized protein. That is, codon translation rates can govern nascent proteome behavior. We emphasize that this pheno...

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Published in:Journal of the American Chemical Society Vol. 136; no. 52; pp. 17892 - 17899
Main Authors: Nissley, Daniel A., O'Brien, Edward P.
Format: Article
Published: American Chemical Society 12/31/2014
Subjects:
Genetic code
Genetic translation
Proteomics
Messenger RNA
Non-equilibrium reactions
Chromosomal translocation
Clustering of particles
Proteins
Online Access:View this record in EBSCOhost