Genotyping of Helicobacter pylori cagA Gene from a Patient Who Failed Eradication Therapy: A Case Report and Review of the Literature.
Helicobacter pylori (H. pylori) is a bacterium that causes chronic gastritis, gastric and duodenal ulcers and gastric cancer. Here we report a female patient presenting with dyspepsia. She was tested positive six times by the Rapid Urease test and Urea breath test (UBT). A culture of gastric biopsy...
| Publicado en: | International Medical Journal Vol. 22; no. 2; pp. 90 - 92 |
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| Autores principales: | , , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Japan International Cultural Exchange Foundation
Apr2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | Helicobacter pylori (H. pylori) is a bacterium that causes chronic gastritis, gastric and duodenal ulcers and gastric cancer. Here we report a female patient presenting with dyspepsia. She was tested positive six times by the Rapid Urease test and Urea breath test (UBT). A culture of gastric biopsy was done and the isolate showed resistance to Clarithromycin and Metronidazole while polymerase chain reaction (PCR) revealed the presence of cagA H. pylori virulence gene. Presence of cagA might not be a risk factor in development of Metronidazole resistance to antibiotic therapy. In conclusion, we report a female Malaysian Indian with cagA positive H. pylori infection, but experienced Metronidazole resistance to antibiotic therapy. |
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