Genotyping of Helicobacter pylori cagA Gene from a Patient Who Failed Eradication Therapy: A Case Report and Review of the Literature.
Helicobacter pylori (H. pylori) is a bacterium that causes chronic gastritis, gastric and duodenal ulcers and gastric cancer. Here we report a female patient presenting with dyspepsia. She was tested positive six times by the Rapid Urease test and Urea breath test (UBT). A culture of gastric biopsy...
| Publicado en: | International Medical Journal Vol. 22; no. 2; pp. 90 - 92 |
|---|---|
| Autores principales: | , , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Japan International Cultural Exchange Foundation
Apr2015
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103113725&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103113725 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13412051 23J1 jtl: International Medical Journal issn: 13412051 maglogo: N pubinfo: dt: Apr2015 vid: 22 iid: 2 pid: 29386 pub: Japan International Cultural Exchange Foundation artinfo: ui: 103113725 103113725 109796373 103113725 ppf: 90 ppct: 2 formats: fmt: @attributes: type: P tig: atl: Genotyping of Helicobacter pylori cagA Gene from a Patient Who Failed Eradication Therapy: A Case Report and Review of the Literature. aug: au: Osman, Hussein Ali Hasan, Habsah Suppian, Rapeah Arjunan, Saravanan B. A., Zilfalil affil: Department of Medical Microbiology and Parasitology, school of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia sug: subj: Dyspepsia Etiology Gastritis Diagnosis Drug Resistance, Microbial Helicobacter Infections Diagnosis Helicobacter Pylori Genotype Antigens, Bacterial Bacterial Proteins Female Adult Polymerase Chain Reaction Adult: 19-44 years Female ab: Helicobacter pylori (H. pylori) is a bacterium that causes chronic gastritis, gastric and duodenal ulcers and gastric cancer. Here we report a female patient presenting with dyspepsia. She was tested positive six times by the Rapid Urease test and Urea breath test (UBT). A culture of gastric biopsy was done and the isolate showed resistance to Clarithromycin and Metronidazole while polymerase chain reaction (PCR) revealed the presence of cagA H. pylori virulence gene. Presence of cagA might not be a risk factor in development of Metronidazole resistance to antibiotic therapy. In conclusion, we report a female Malaysian Indian with cagA positive H. pylori infection, but experienced Metronidazole resistance to antibiotic therapy. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|