Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers.

Purpose: The aim of the study was to determine the steady-state pharmacokinetics of metformin in healthy volunteers with different numbers of reduced-function alleles in the organic cation transporter 1 gene ( OCT1). Methods: The study was conducted as part of a randomized cross-over trial. Thirty-f...

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Detalles Bibliográficos
Publicado en:European Journal of Clinical Pharmacology Vol. 71; no. 6; pp. 691 - 698
Autores principales: Christensen, Mette, Højlund, Kurt, Hother-Nielsen, Ole, Stage, Tore, Damkier, Per, Beck-Nielsen, Henning, Brøsen, Kim
Formato: clinical trial research tables/charts Journal Article
Publicado: Springer Nature Jun2015
Acceso en línea:Ver este registro en EBSCOhost