Radiolabeled RGD tracer kinetics annotates differential αvβ 3 integrin expression linked to cell intrinsic and vessel expression.

Purpose: The purpose of this paper is to study the association between RGD binding kinetics and αvβ3 integrin receptor density in the complex tumor milieu.Procedures: We assessed αvβ3 in vitro and by (68)Ga-DOTA-[c(RGDfK)]2 positron emission tomography (PET) in tumors with varying αvβ3.Results: Intr...

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Detalles Bibliográficos
Publicado en:Molecular Imaging & Biology Vol. 16; no. 4; pp. 558 - 567
Autores principales: Alam, Israt S, Witney, Timothy H, Tomasi, Giampaolo, Carroll, Laurence, Twyman, Frazer J, Nguyen, Quang-Dé, Aboagye, Eric O
Formato: research Journal Article
Publicado: Springer Nature Aug2014
Acceso en línea:Ver este registro en EBSCOhost