Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters.

Background: 4-1BB, a member of the TNF receptor superfamily, has a role in various inflammatory pathologies through its interaction with 4-1BB ligand. We previously demonstrated that it participates in initiating and promoting obesity-induced adipose inflammation in a rodent model.Objective: In this...

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Bibliographic Details
Published in:International Journal of Obesity Vol. 38; no. 8; pp. 1075 - 1083
Main Authors: Tu, T H, Kim, C-S, Kang, J-H, Nam-Goong, I S, Nam, C W, Kim, E S, Kim, Y I, Choi, J I, Kawada, T, Goto, T, Park, T, Yoon Park, J H, Choi, M-S, Yu, R
Format: research Journal Article
Published: Springer Nature Aug2014
Online Access:View this record in EBSCOhost