Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters.
Background: 4-1BB, a member of the TNF receptor superfamily, has a role in various inflammatory pathologies through its interaction with 4-1BB ligand. We previously demonstrated that it participates in initiating and promoting obesity-induced adipose inflammation in a rodent model.Objective: In this...
| Published in: | International Journal of Obesity Vol. 38; no. 8; pp. 1075 - 1083 |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | research Journal Article |
| Published: |
Springer Nature
Aug2014
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| Online Access: | View this record in EBSCOhost |