Increased bioavailability of phenylephrine by co-administration of acetaminophen: results of four open-label, crossover pharmacokinetic trials in healthy volunteers.

Purpose: Over-the-counter combinations containing acetaminophen and phenylephrine for treatment of the common cold and influenza are widespread, but there are few data about pharmacokinetics of these two drugs used in combination. We aimed to investigate pharmacokinetic interactions between acetamin...

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Bibliographic Details
Published in:European Journal of Clinical Pharmacology Vol. 71; no. 2; pp. 151 - 159
Main Authors: Atkinson, Hartley, Stanescu, Ioana, Salem, Isam, Potts, Amanda, Anderson, Brian
Format: research tables/charts randomized controlled trial Journal Article
Published: Springer Nature Feb2015
Online Access:View this record in EBSCOhost